About: Dermatologic Complication is a research topic. Over the lifetime, 65 publications have been published within this topic receiving 784 citations.
TL;DR: In this paper, the authors examined the dermatologic and mucosal problems associated with mammalian target of rapamycin inhibitor use, and provided personal experiences regarding the management and treatment of these adverse events.
Abstract: Mammalian target of rapamycin inhibitor use is associated with numerous adverse events, including dermatologic and mucosal problems. Awareness of these complications, which clinically manifest across a severity spectrum from minor through severe and may occur at varied time points after initiation of sirolimus therapy, can be useful to clinicians in both managing these events and determining the appropriate intervention(s) for patients. This manuscript examines the dermatologic and mucosal problems associated with mammalian target of rapamycin inhibitor use, reviews the literature, and provides personal experiences regarding the management and treatment of these adverse events.
TL;DR: Patients with venous insufficiency commonly develop complications which can result in significant morbidity and occasional mortality, but other complications may arise including dermatitis, atrophie blanche, lipodermatosclerosis, and malignancy.
TL;DR: Cutaneous disorders occur with great frequency in patients with HIV infection and increase in number and severity as the disease progresses and immune function declines In addition, the first findings related to HIV infection are often on the skin Cutaneous infections with herpesviruses may be severe and atypical in their presentations; papillomaviruses and MC are common as well Bacterial infections may be primary or secondary to other skin diseases; superficial and deep fungal infections are also prevalent Papulosquamous disorders, including seborrheic dermatitis, psoriasis, and eczema
TL;DR: Cutaneous complications of PDT included serious phototoxicity requiring oral corticosteroid treatment, herpes zoster requiring hospitalization and intravenous antiviral treatment, and erythema multiforme drug reaction related to porfimer sodium.
Abstract: Photodynamic therapy (PDT) has several cutaneous complications: photosensitivity is well known, but the other complications are rarely reported, Since late 1997, we have studied the dermatologic complications of using porfimer sodium PDT to treat either Barrett esophagus with high-grade dysplasia or gastroesophageal cancer in 72 consecutive patients. Cutaneous complications of PDT included serious phototoxicity requiring oral corticosteroid treatment (22 patients; 31%), herpes zoster (HZ) requiring hospitalization and intravenous antiviral treatment (1 patient; 1%), and erythema multiforme drug reaction related to porfimer sodium (1 patient; 1%). PDT-associated dermatologic complications were common and were not related to cutaneous photosensitivity.