Topic
COX6A1
About: COX6A1 is a research topic. Over the lifetime, 11 publications have been published within this topic receiving 280 citations. The topic is also known as: COX6A & COX6AL.
Papers
TL;DR: It is concluded that subunit COX VIa-L is synthesized as a preprotein, as are other COX subunits, and that this subunit gene is regulated by neuronal activity.
29 citations
TL;DR: The results demonstrate that yeast-based functional screening of human genes for inhibitors of Bax-sensitivity in yeast identified a protein that not only suppresses the toxicity of BAX in yeast, but also has a potential role in protecting mammalian cells from 4-HPR-induced apoptosis.
27 citations
TL;DR: It is concluded that Sp1, NRF-1, andNRF-2 are important in activating transcription of the rat COX6A1 gene.
23 citations
TL;DR: Primer extension and ribonuclease protection assays were used to map the 5' ends of COX6A1 transcripts in heart; both methods identified several clusters of transcription initiation sites, indicating that COX 6A1 mRNA is heterogeneous at the 5', indicating that the bovine gene for the nuclear-encoded heart/muscle isoform of cytochrome c oxidase subunit VIa
22 citations
1 Jan 2009
TL;DR: The NRC Beef Cattle Model was utilized to predict feed intake based on observed gain (and gain based on observations) and the difference between this NRC-predicted feed intake and observed intake is termed model predicted residual consumption (MPRC).
Abstract: Feed efficiency is an economically important trait that is likely influenced by complex molecular mechanisms. We utilized the NRC Beef Cattle Model to predict feed intake based on observed gain (and gain based on observed intake), where the NRC model also accounts for breed type, sex and season. The difference between this NRC-predicted feed intake and observed intake is termed model predicted residual consumption (MPRC). Associations between feed efficiency and mitochondrial respiration have been previously reported in the literature. From a study of 177 animals, RNA was extracted from liver samples from 18 animals at each extreme of the MPRC tails (36 samples). Following microarray analysis, quantitative realtime RT-PCR (qPCR) was used to examine expression of several respiratory complex genes including mitochondrial genes COX1, COX2, COX3 (Complex IV) and CYTB (Complex III), and nuclear genes COX4, COX6A1, COX7A2, COX7B, COX7C (Complex IV), SHDB (Complex II) and NQO2 (Complex I). Although expression for some genes was influenced by sire and family, no relationship between expression of any of these genes was found to be associated with feed efficiency phenotype.
4 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 2 |
| 2020 | 1 |
| 2014 | 1 |
| 2010 | 2 |
| 2009 | 1 |
| 2008 | 1 |