TL;DR: The Copaiba Oil from Copaifera multijuga Hayne (100 mg/kg) was the most potent, inhibiting both NO production and the pleurisy induced by zymosan, and the oleoresins from CopAifera cearensis Huber ex Ducke and Copaifiera reticulata Ducke were also able to inhibit NOProduction and the Pleurisy but with less intensity.
TL;DR: This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.
Abstract: Copaiba oleoresins are exuded from the trunks of trees of the Copaifera species (Leguminosae-Caesalpinoideae). This oleoresin is a solution of diterpenoids, especially, mono- and di-acids, solubilized by sesquiterpene hydrocarbons. The sesquiterpenes and diterpenes (labdane, clerodane and kaurane skeletons) are different for each Copaifera species and have been linked to several reported biological activities, ranging from anti-tumoral to embriotoxic effects. This review presents all the substances already described in this oleoresin, together with structures and activities of its main terpenoids.
TL;DR: This work compared the antinociceptive activity of two Amazonian Copaiba oils administered by oral route using peripheral, spinal, spinal and supra-spinal models to indicate that CopAiba oils demonstrate peripheral and central antinOCiceptive effect.
TL;DR: It is suggested that a small investment in cutting lianas can greatly increase wood production in degraded cativo forests, regardless of severity of prior liana infestation.