Topic
Compound eye morphogenesis
About: Compound eye morphogenesis is a research topic. Over the lifetime, 4 publications have been published within this topic receiving 132 citations.
Papers
TL;DR: This chapter is an informal, speculative essay on the emergence of form during Drosophila eye development and the forces that impress this form and reviews selected events of retinal morphogenesis and considers mechanisms potentially responsible.
Abstract: D’Arcy Thompson’s 1917 treatise, On Growth and Form, articulated what might reasonably be considered the First Law of Morphogenesis: “... the form of an object is a ‘diagram of forces’... which have been impressed upon it...” (Thompson 1917). This chapter is an informal, speculative essay on the emergence of form during Drosophila eye development and the forces that impress this form. It reviews selected events of retinal morphogenesis and considers mechanisms potentially responsible. In most instances, the molecular basis of morphogenesis in the eye is poorly understood; in many cases, correlation and causality remain to be distinguished. An integrated, realistic force diagram of the fly eye lies in the future.
29 citations
1 Feb 1990
TL;DR: It is found that the initial clustering of photoreceptor cells is affected in eye imaginal discs of spl larvae causing the defects visible in the adult eye and that the other abnormalities are morphogenetic consequences of the defective cell grouping.
Abstract: The spl mutation of the N gene causes, among other phenotypic traits, the lack of a few ommatidia, roughness and a general reduction in the size of the compound eye; these defects are drastically enhanced by the dominant mutation E(spl)
D. We have studied cellular and developmental aspects of the phenotypic interaction between spl and E(spl)
D. We found that the initial clustering of photoreceptor cells is affected in eye imaginal discs of spl larvae causing the defects visible in the adult eye. The degree of disorganization of the spl/Y; E(spl)
D/ + eye disc is much higher, only a few photoreceptor cells are able to group with representatives of the other cell types and differentiate normally. BrdU incorporation shows that the proliferation pattern of the spl/Y; E(spl)
D/ + disc cells during the third instar is normal. Abundant cell death occurs posteriorly in the mutant discs, which accounts for their small size. Finally, we found that in the eye imaginal disc the transcription of m8, the E(spl) gene, responsible for the enhancement of the spl phenotype caused by the E(spl)
D mutation, is restricted to the morphogenetic furrow, where the ommatidial cells start grouping with each other to take on their future developmental fates; the m8 transcription rate is highly increased in E(spl)
D eye discs. All these observations indicate that the assembly of the ommatidial cells is affected in the spl/Y; E(spl)
D/ + disc and that the other abnormalities are morphogenetic consequences of the defective cell grouping.
22 citations
TL;DR: In photoreceptor neurons, myosin-II is undetectable at the apical domain throughout the first half of pupal life, at which time this membrane domain is involuted into the epithelium and progresses toward the retinal floor, and the spatiotemporal pattern of myosIn-II localization and the morphological defects observed in the eyes of a myosIN-II mutant suggest that the myos in-II/F-actin system is involved in
1 Jan 2002
TL;DR: Retinal Specification and Determination in Drosophila Regulators of the Morphogenetic Furrow and the Establishment of Retinal Connectivity are studied.
Abstract: Retinal Specification and Determination in Drosophila * Regulators of the Morphogenetic Furrow * NOTCH and the Patterning of Ommatidial Founder Cells in the Developing Drosophila Eye * The Epidermal Growth Factor Receptor in Drosophila Eye Development * Cell Fate Specification in the Drosophila Eye * Tissue Polarity in the Retina * Regulation of Growth and Cell Proliferation During Eye Development * Evolution of Color Vision * Developmental Regulation Through Protein Stability * Programmed Death in Eye Development * Drosophila Compound Eye Morphogenesis: Blind Mechanical Engineers? The Establishment of Retinal Connectivity * Homologies Between Vertebrate and Invertebrate Eyes * Applications of the Drosophila Retina to Human Disease Modeling.
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2004 | 1 |
| 2002 | 2 |
| 1990 | 1 |