Topic
Complex Tic
About: Complex Tic is a research topic. Over the lifetime, 12 publications have been published within this topic receiving 206 citations.
Papers
TL;DR: The hypothesis that TS+OCD is a more severe form of TS is supported and that comorbid OCD/OCB, depression, and anxiety belong to the TS spectrum, while ADHD should be better conceptualized as a separate problem.
Abstract: Background: Gilles de la Tourette syndrome (TS) is a complex neuropsychiatric disorder defined by the presence of motor and phonic tics, but often associated with psychiatric comorbidities. The main objective of this study was to explore the clinical presentation and comorbidities of TS. Method: We analyzed clinical data obtained from a large sample (n=1032; 529 children and 503 adults) of patients with tic disorders from one single German TS center assessed by one investigator. Data was collected with the help of an expert-reviewed semi-structured interview, designed to assess tic severity and certain comorbidities. Group comparisons were carried out via independent sample t-tests and chi-square tests. Results: The main findings of the study are: (1) tic severity is associated with the presence of premonitory urges (PU), copro-, echo-, and paliphenomena and the number of comorbidities, but not age at tic onset; it is higher in patients with comorbid obsessive-compulsive disorder (OCD) than in patients with comorbid attention deficit/hyperactivity disorder (ADHD). (2) PU were found to be highly associated with “not just right experiences” and to emerge much earlier than previously thought alongside with the ability to suppress tics (PU in >60% and suppressibility in >75% at age 8-10 years). (3) Self-injurious behavior (SIB) is highly associated with complex motor tics and coprophenomena, but not with OCD/ obsessive-compulsive behavior (OCB). While comorbid ADHD is associated with a lower ability to suppress tics, comorbid depression is associated with sleeping problems. Discussion: Our results demonstrate that tic severity is not influenced by age at onset. From our data, it is suggested that PU represent a specific type of “not just right experience” that is not a prerequisite for tic suppression. Comorbid ADHD reduces patients’ ability of successful tic suppression. Our data suggest that SIB belongs to the coprophenomena spectrum and hence should be conceptualized as a complex tic rather than a compulsion. Finally, this study strongly supports the hypothesis that TS+OCD is a more severe form of TS and that comorbid OCD/OCB, depression, and anxiety belong to the TS spectrum, while ADHD should be better conceptualized as a separate problem.
126 citations
TL;DR: It is hypothesized that this exercising of the sensorimotor cortex resulted in increased activation of this cerebrocortical subsystem and was reflected in increased voluntary muscle control and a heightened threshold for random motor discharge, resulting in the elimination of both tics as in the response of cases of epilepsy with motor involvement to EEG sensorsimotor rhythm biofeedback training.
38 citations
TL;DR: In three patients tics were quantitatively analyzed in a psychophysiological study employing serial polygraphic analysis, a variety of psychological factors involved in these differing placebo effects were considered responsible for both beneficial and ineffectual drug influences.
Abstract: In three patients tics were quantitatively analyzed in a psychophysiological study employing serial polygraphic analysis. Two classes of tic were described both electrophysiologically and clinically. The simple tic was thought to reflect a basic neurophysiological disorder. The complex tic, (possibly a derivative of the simple variety) carried psychological significance. A doubleblind placebo controlled drug study using haloperidol indicated that while the administration of the drug was associated with a significant reduction of total tics, the drug was associated with either positive or negative placebo influences on the frequency of complex tics. A variety of psychological factors involved in these differing placebo effects were considered responsible for both beneficial and ineffectual drug influences. Both intrapsychic and territorial restraint were suggested as specifically significant in the genesis of the complex tic.
27 citations
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TL;DR: Tics are the most common movement disorder of childhood and the majority of tremors in the pediatric age group are due to underlying metabolic, endocrine, or heredodegenerative disorders.
23 citations
TL;DR: In this article, the authors investigated the tribological behavior of TiC/TaC reinforced NiCrMo and Mo plasma sprayed coatings with respect to friction and wear behavior in pin-on-disk tests.
23 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2016 | 1 |
| 2001 | 1 |
| 2000 | 1 |
| 1995 | 1 |
| 1986 | 1 |