TL;DR: It was found that for the different radiopharmaceuticals, the effective dose equivalent per activity unit administered extends over an interval of five orders of magnitude, from 0.00015 to 20 mSv/MBq.
Abstract: The concept of “effective dose equivalent”, which was introduced by the International Commission on Radiological Protection (ICRP) for occupationally exposed workers, has also created the possibility of expressing by means of a single figure, the radiation risk to patients undergoing different medical radiodiagnostic procedures. In this study, we present the effective dose equivalent for various nuclear-medicine investigations. The figures given are primarily based on a review of data contained in the literature on the mean absorbed dose to various organs. In many cases, however, our own calculations, using biokinetic data derived from the literature, have been used.
TL;DR: The calculated annual effective dose values due to the ingestion of (226)Ra in the Awujale, Ake, Saboab, Alagbon, Alapora and Totoro samples exceeded International Commission on Radiological Protection limit of 1.0 mSv y(-1) for individual public exposure.
Abstract: Activity concentrations of (40)K, (226)Ra, (228)Ac and (235)U were measured in 11 dug and 9 drilled well water samples from 3 large cities in Ogun state, Southwestern Nigeria, consumed by the population living in the cities. The measurement was done using co-axial type high-purity germanium (HPGe) detector (Canberra Industries Inc.). The measured activity concentrations in the water samples ranged from 1.74 +/- 1.83 to 4.69 +/- 0.17 Bq l(-1); 2.89 +/- 0.62 to 7.79 +/- 7.22 Bq l(-1); 0.35 +/- 0.07 to 1.17 +/- 0.40 Bq l(-1) and 0.18 +/- 0.05 to 4.77 +/- 0.34 Bq l(-1) for (40)K, (226)Ra, (228)Ac and (235)U, respectively. Total annual effective dose rates from the ingestion of these radionuclides in the untreated wells were estimated using measured activity concentrations in the radionuclides and their ingested dose conversion factors. Estimated annual effective dose rates ranged from 0.04 to 6.82; 0.01 to 1.36 and 0.01 to 1.49 mSv y(-1) for age groups or =17 y, respectively. Committed dose for age group > or =17 y ranged from 8.8 x 10(-4) to 8.9 x 10(-2) Sv. The calculated annual effective dose values due to the ingestion of (226)Ra in the Awujale, Ake, Saboab, Alagbon, Alapora and Totoro samples exceeded International Commission on Radiological Protection limit of 1.0 mSv y(-1) for individual public exposure. These wells are recommended for treatment that would remove radium from their waters.
TL;DR: Computer simulations suggest that little radiological risk is associated to the use of depleted uranium weapons, and the greatest hazard is related to the water contamination in conditions of effective leaching of uranium in the groundwater.
Abstract: Several weapons used during the recent conflict in Yugoslavia contain depleted uranium, including missiles and armor-piercing incendiary rounds. Health concern is related to the use of these weapons, because of the heavy-metal toxicity and radioactivity of uranium. Although chemical toxicity is considered the more important source of health risk related to uranium, radiation exposure has been allegedly related to cancers among veterans of the Balkan conflict, and uranium munitions are a possible source of contamination in the environment. Actual measurements of radioactive contamination are needed to assess the risk. In this paper, a computer simulation is proposed to estimate radiological risk related to different exposure scenarios. Dose caused by inhalation of radioactive aerosols and ground contamination induced by Tomahawk missile impact are simulated using a Gaussian plume model (HOTSPOT code). Environmental contamination and committed dose to the population resident in contaminated areas are predicted by a food-web model (RESRAD code). Small values of committed effective dose equivalent appear to be associated with missile impacts (50-y CEDE < 5 mSv), or population exposure by water-independent pathways (50-y CEDE < 80 mSv). The greatest hazard is related to the water contamination in conditions of effective leaching of uranium in the groundwater (50-y CEDE < 400 mSv). Even in this worst case scenario, the chemical toxicity largely predominates over radiological risk. These computer simulations suggest that little radiological risk is associated to the use of depleted uranium weapons.
TL;DR: The determination of 234U and 238U content in drinking waters treated at four treatment plants supplying water to a set of municipalities located in northern Spain has given mean values of 1.14 mBq/L and 0.081 microSv/person, respectively, taking into account the population supplied with water and its distribution in age intervals.
TL;DR: The radiation committed dose and the radioiodine activity to administer were calculated using a new, very simple algorithm and a comparison between the values calculated by this new algorithm and the old, classical Marinelli-Quimby algorithm shows that the new method is more accurate.
Abstract: Substantial reduction in the thyroid volume (up to 70-80%) after 131 I therapy of Graves' disease has been demonstrated and reported in the literature. Recently a mathematical model of thyroid mass reduction during the first month after therapy has been developed and a new algorithm for the radiation committed dose calculation has been proposed. Reduction of the thyroid mass and the radiation committed dose to the gland depend on a parameter k, defined for each subject. The calculation of k allows the prediction of the activity to administer, depending on the radiation committed dose chosen by the physician. In this paper a method for calculating k is proposed. The calculated values of k are compared to values derived from measurements of the changes in thyroid mass in twenty-six patients treated by 131 I for Graves' disease. The radiation committed dose to the thyroid can be predicted within 21%, and the radioiodine activity to administer to the patient can be predicted within 22% using the calculated values of k. The thyroid volume reduction during the first month after therapy administration can be also predicted with good accuracy using the calculated values of k. The radiation committed dose and the radioiodine activity to administer were calculated using a new, very simple algorithm. A comparison between the values calculated by this new algorithm and the old, classical Marinelli-Quimby algorithm shows that the new method is more accurate.