Topic
Chromatographic response function
About: Chromatographic response function is a research topic. Over the lifetime, 77 publications have been published within this topic receiving 2031 citations.
Papers published on a yearly basis
Papers
TL;DR: In this article, a general scheme combines the Snyder solvent selectivity-triangle concept with a mixture-design statistical technique to optimize the strength and selectivity of mobile phase solvents for reversed-phase liquid chromatography (LC) separations.
466 citations
TL;DR: In this article, the modified sequential simplex algorithm was used as the basis for the unattended optimisation of reversed-phase liquid chromatographic separations and a chromatogram response function was computed to evaluate individual chromatograms with respect to resolution and analysis time.
176 citations
TL;DR: In this article, the stepwise procedure described previously for the selection of optimal mobile phase compositions in reversed phase liquid chromatography (RPLC) is improved in two ways: the optimization criterion is modified to account for variations in analysis time, and the iterative approach to the optimal solvent composition makes a more efficient use of previous data.
Abstract: The stepwise procedure described previously [1] for the selection of optimal mobile phase compositions in reversed phase liquid chromatography (RPLC) is improved in two ways. The optimization criterion is modified to account for variations in analysis time. The iterative approach to the optimal solvent composition makes a more efficient use of previous data. An example illustrates the resulting gain in speed and accuracy.
147 citations
TL;DR: The utility of the sequential simplex method in chromatographic methods development is demonstrated by the experimental optimization of separation for several mixtures of isomeric octanes in this article, where the oven temperature and carrier gas flow-rate are varaied simultaneously during the optimization process.
140 citations
TL;DR: In this paper, the desirability function, a multi-criterion decision-making method proposed by Derringer, was investigated to optimize different chromatographic performance goals.
104 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2020 | 1 |
| 2017 | 2 |
| 2015 | 2 |
| 2014 | 1 |
| 2013 | 2 |