TL;DR: This new polypropylene suture with suitable antimicrobial features appears to be a promising macromolecular material for clinical and cosmetic applications.
Abstract: Polypropylene sutures (PP) are already used in surgery. Because microbial infection leads to complications, we developed antimicrobial PP suture by plasma-induced graft polymerization of acrylic acid followed by chitosan binding on the remaining carboxyl groups. Mechanical properties and surface morphologies were analyzed on these sutures. Tetracycline hydrochloride (TC) or nanosilver (NS) was then immobilized to PP. The resulting PP sutures evidenced drug release properties and antimicrobial activity in vitro. PP implanted in vivo for 30 days in the muscle of rats showed the absence of adverse effects and a tissue organization. This new polypropylene suture with suitable antimicrobial features appears to be a promising macromolecular material for clinical and cosmetic applications.
TL;DR: A fluorescent binding assay was developed to investigate the effects of mutagenesis on the binding affinity and substrate specificity of the chitin-binding domain of chit inase A1 from Bacillus circulans WL-12 and found that mutation T682A led to a higher specificity towards chitinous substrates than the wildtype.
TL;DR: It is demonstrated by means of DLS that the DNA-chitosan complexation is favored at acidic conditions considering that fewer amounts of chitOSan were required to compact the DNA.
TL;DR: In this paper, an ion imprinted magnetic chitosan (IMCS) was synthesized through co-precipitation using steel pickling waste liquor and chitonsan and Cu(II) as template ions, which was then characterized by TEM, SEM, EDX, FTIR, XRD and VSM.
Abstract: To reduce costs and improve practicability, an ion imprinted magnetic chitosan (IMCS) was synthesized through co-precipitation using steel pickling waste liquor and chitosan and Cu(II) as template ions, which was then characterized by TEM, SEM, EDX, FTIR, XRD and VSM. The batch experiments were carried out for its potential application and high selectivity of Cu(II) removal, which were observed due to the paramagnetic properties and coordination reactions in the imprinted cavities. Kinetic studies revealed that the adsorption process followed a pseudo second-order model and the equilibrium data fit perfectly with the Langmuir isotherm model. The maximum adsorption capacity was 109.89 mg g−1. Negative values for ΔH0 and ΔG0 indicated an exothermic and spontaneous adsorption process. The adsorption process was found to be a chemical reaction and coordination complexes were formed between the metal ions and the groups of chitosan binding mainly in the “bridge model”. Moreover, 0.2 mol L−1 HCl solution was considered as the most appropriate eluent for regeneration. It showed a great performance in the experiments for practical copper wastewater and the process was considerably cost-effective.
TL;DR: Oxygen and carbon dioxide plasma treatments were applied in order to study their influences on chitosan adhesion onto PET foils in this article, which led to a decrease in accessible protonated amino groups.