Centaurea pullata

Abstract: The aerial parts of Centaurea pullata afforded, in addition to the previously isolated sesquiterpene lactones, 11β,13-dihydrocnicin and 11β,13-dihydro-19-desoxycnicin, three minor sesquiterpene lactones, namely, a new germacranolide, 8α-O-(4-acetoxy-5-hydroxyangeloyl)-11β,13-dihydrocnicin, and two new eudesmanolides, 8α-O-(4-hydroxy-2-methylenebutanoyloxy)-11β,13-dihydrosonchucarpolide and 8α-O-(4-hydroxy-2-methylenebutanoyloxy)-11β,13-dihydro-4-epi-sonchucarpolide. The in vitro antimicrobial activity of all isolated sesquiterpene lactones was tested against six bacteria and eight fungal species, using a microdilution method. All compounds tested showed greater antibacterial and antifungal activities than the positive controls used.

Abstract: The volatile composition of Centaurea pullata L., C. grisebachii (Nyman) Heldr. subsp. grisebachii and C. affinis Friv. have been studied. The essential oils were obtained by hydrodistillation in a modified Clevenger-type apparatus, and their analyses were performed by GC and GC-MS. Identification of the components was made by comparison of mass spectra and retention indices with literature records and by co-chromatography with authentic compounds. Their main constituents were caryophyllene oxide for C. pullata, 6,10,14-trimethyl pentadecan-2-one and spathulenol for C. grisebachi subsp. grisebachii, thymol and dodecanol for C. affinis. The essential oils were evaluated for their antimicrobial potential and showed a moderate activity against all microorganisms tested.

Abstract: Achillea millefolium (Anthemideae), Centaurea aspera L., Centaurea pullata Centaurea son-chifolia (Cardueae), Gerbera jamesonii Leibnitzia anandria (Mutisieae). Xeranthemum cylindraceum (Cardueae) Anthemis altissima, Anthemis cairica (Anthemideae) Chardinia orientalis (Cardueae) Aster ptarmicoides (Astereae) Dimorphotheca pluvialis (Calenduleae)