Topic
Celastrus
About: Celastrus is a research topic. Over the lifetime, 56 publications have been published within this topic receiving 854 citations.
Papers published on a yearly basis
Papers
TL;DR: It is demonstrated that celastrol derived from Celastrus has potent anti-arthritic activity using the rat adjuvant-induced arthritis model of human RA, and this results provide a strong rationale for further testing and validation of the use of Celastrol and the natural plant extract from celastrus as an adjunct (with conventional drugs) or alternative modality for the treatment of RA.
108 citations
TL;DR: Celastrus and celastrol controlled inflammation-induced bone damage by modulating the osteoimmune cross-talk in the adjuvant-induced arthritis model of RA and are promising adjuncts to conventional drugs for arthritis treatment.
85 citations
67 citations
TL;DR: Biological evaluation showed that Maytenfolone-A demonstrated cytotoxicity against hepatoma and nasopharynx carcinoma, and celasdin-B was found to exhibit anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 0.8 microgram ml-1.
61 citations
TL;DR: Pristimerin and celastrol isolated from the roots of Celastrus hypoleucus (Oliv) Warb f argutior Loes exhibited inhibitory effects against diverse phytopathogenic fungi.
Abstract: Pristimerin and celastrol isolated from the roots of Celastrus hypoleucus (Oliv) Warb f argutior Loes exhibited inhibitory effects against diverse phytopathogenic fungi. Pristimerin and celastrol were found to inhibit the mycelial growth of Rhizoctonia solani Kuhn and Glomerella cingulata (Stonem) Spauld & Schrenk in vitro by 83.6 and 62.6%, respectively, at 10 mug ml(-1). Pristimerin showed good preventive effect (96.7% at 100 mug ml(-1)) and curative effect (66.5% at 100 mug ml(-1)) against wheat powdery mildew in vivo. For celastrol, the preventive and curative effects against wheat powdery mildew were 80.S and 45.4%, respectively, at 100 mugml(-1). (C) 2004 Society of Chemical Industry.
56 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2020 | 3 |
| 2019 | 2 |
| 2017 | 3 |
| 2016 | 3 |
| 2015 | 2 |
| 2014 | 4 |