TL;DR: Incoranone showed cytotoxic activity against human leukaemia cells and was determined as 11,12,14,16-tetrahydroxyl-17(15 → 16)- abeo -abieta-8,11,13-trien-one.
TL;DR: Pollen morphology and correlated variation in floral and fruit morphology suggest that Caryopteris comprises three primary phenetic groups, but two recent cladistic analyses indicate that the genus is para- or polyphyletic and that only one of the three phenetic subgroups is clearly monophyletic.
Abstract: Caryopteris, an Asian genus of 16 species, has greater pollen diversity than has been reported in any other genus of Labiatae. The pollen morphology of 15 species is documented here. Three pollen types are distinguished on the basis of exine structure and sculpturing: spinulose to spinose with slender, finely divided columellae (alternatively interpretable as an expanded tectum); verrucate with a well defined tectum and thick, sparsely branched columellae; and suprareticulate to microreticulate with moderately thick, sparsely branched columellae. Thirteen species are tri- colpate, Caryopteris divaricata is triporate, and C. nepalensis is 6-pantocolpate. Pollen morphology and correlated variation in floral and fruit morphology suggest that Caryopteris comprises three primary phenetic groups. However, two recent cladistic analyses (one based in part on the pollen features documented here) indicate that the genus is para- or polyphyletic and that only one of the three phenetic subgroups is clearly monophyletic. Recircumscription of the genus is recommended, but this should await completion of current studies that will facilitate its subdivision into monophyletic taxa.
TL;DR: Five new iridoid glucoside derivatives, three new diterpenoids, and 11 known compounds were isolated from the aqueous EtOH extract of Caryopteris glutinosa, and cell-based estrogen biosynthesis assays indicated that caryopteriside C and carypterisoid B promote the biosynthesis of estrogen E2.
Abstract: Five new iridoid glucoside derivatives (1–5), three new diterpenoids (7, 12, and 15), and 11 known compounds were isolated from the aqueous EtOH extract of Caryopteris glutinosa. Cell-based estrogen biosynthesis assays indicated that caryopteriside C (3) and caryopterisoid B (12) promote the biosynthesis of estrogen E2, with EC50 values of 11.1 and 8.0 μM, respectively, in human ovarian granulosa-like KGN cells via upregulating the expression of aromatase.
TL;DR: Eleven abietane-type diterpenoids and two known abietanes were isolated from the roots of Caryopteris mongolica, and their structures were characterized to estimate the preventive effects of the isolates for neurodegenerative disease development and their inhibitory activities against acetylcholinesterase from human erythrocytes and horse serum were evaluated.
TL;DR: To identify antibacterial components in traditional Mongolian medicinal plant Caryopteris mongolica, an ortho-quinone abietane caryopteron A and three its derivatives carypteron B-D were isolated from the roots of the plant together with three known abietanes demethylcryptojaponol (5), 6α-hydroxydemethyl cryptojaponsol (6), and 14-deoxycoleon U (7).