Topic
Carbohydrazide
About: Carbohydrazide is a research topic. Over the lifetime, 888 publications have been published within this topic receiving 8140 citations. The topic is also known as: diaminourea & carbonodihydrazide.
Papers published on a yearly basis
1 / 2
Papers
TL;DR: In this paper, 3-(2-methylbenzimidazol-1-yl)propanoic acid hydrazide (1) with CS2/KOH gave oxadiazole 2 which underwent Mannich reaction to give triazole 4 which was treated with both aldehydes and acetic anhydride to give 5 and 6, respectively.
Abstract: Reaction of 3-(2-methylbenzimidazol-1-yl)propanoic acid hydrazide (1) with CS2/KOH gave oxadiazole 2 which underwent Mannich reaction to give 3. Compound 2 was treated with hydrazine hydrate to give triazole 4 which was treated with both aldehydes and acetic anhydride to give 5 and 6, respectively. Carbohydrazide 1 was reacted with ethyl acetoacetate, acetylacetone and aldehydes to give 7, 8 and 9, respectively. Cyclocondensation of 9 with thioglycolic and thiolactic acids gave 10 and 11, respectively. Some of these compounds showed potential antimicrobial activities.
362 citations
TL;DR: A series of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives were synthesized and the effects of all the compounds on A549 cell growth were investigated, showing that all compounds had almost inhibitory effects on the growth of A549 cells.
214 citations
189 citations
TL;DR: Design and synthesis of Schiff bases of nalidixic acid carbohydrazide and isatin derivatives and their Structures of the synthesized derivatives were confirmed on the bases of spectral methods of analyses, showing the necessity of the following pharmacophoric features for anti-TB activity.
169 citations
TL;DR: In this article, a new crystal, (E)-N’-(4-(dimethylamino)benzylidene)-5-methyl-1H-pyrazole-3-carbohydrazide (3) has been synthesized and characterized by FT-IR, NMR, ESI-MS and single crystal X-ray diffraction (XRD).
159 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 25 |
| 2024 | 35 |
| 2023 | 45 |
| 2022 | 66 |
| 2021 | 29 |
| 2020 | 39 |