Topic
CAP-e
About: CAP-e is a research topic. Over the lifetime, 2 publications have been published within this topic receiving 33 citations. The topic is also known as: cell-based antioxidant protection in erythrocytes.
Papers
TL;DR: In ex vivo cellular antioxidant capacity of Cap-e and ORAC assays, HAHZB showed remarkable free radical scavenging ability in a dose dependent manner and highlights interaction between diabetes, oxidative stress and inflammation.
22 citations
TL;DR: Both PC and the non-PC fraction contributed to the antioxidant properties and anti-inflammatory effects, without a negative impact on blood clotting in vitro, suggesting a potential benefit for the consumable ACE extract in assisting the reduction of inflammatory conditions.
Abstract: The goal for this work was to characterize basic biological properties of a novel Arthrospira platensis-based aqueous cyanophyta extract (ACE), enriched in the known anti-inflammatory cyclooxygenase-2 (COX-2) inhibitor phycocyanin (PC), but also containing a high level of non-PC bioactive compounds. Antioxidant properties were tested in parallel in the Folin–Ciocalteu assay (chemical antioxidant capacity) and in the cellular antioxidant protection (CAP-e) bioassay, where both the PC and the non-PC fractions contributed to the antioxidant capacity and CAP of ACE. In contrast to the COX-2 inhibition seen in the presence of PC, the inhibition of enzymatic activity of the inflammatory mediator Lipoxygenase was associated specifically with the non-PC fraction of ACE. Inhibition of formation of reactive oxygen species (ROS) was evaluated using polymorphonuclear cells from healthy human donors. The inhibition of ROS formation was seen for both the PC and non-PC fractions, with ACE showing the most robus...
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2020 | 1 |
| 2015 | 1 |