Topic
Bone spavin
About: Bone spavin is a research topic. Over the lifetime, 51 publications have been published within this topic receiving 625 citations.
Papers published on a yearly basis
Papers
TL;DR: Tiludronate treatment is proven to be effective in bone spavin in horses in association with a controlled exercise programme and offers an alternate medical treatment for bone sp Gavin.
Abstract: Summary
Reasons for performing study: Tiludronate regulates bone remodelling through a decrease of the resorptive process and should therefore ameliorate the remodelling processes active in osteoarthritis of the distal tarsal joints (‘bone spavin’) and alleviate pain associated with abnormal bone lysis.
Objective: To confirm the efficacy of tiludronate, administered as a single infusion at a dose of 1 mg/kg bwt, in the treatment of bone spavin in the horse.
Methods: A double blind placebo controlled trial on 108 clinical cases of bone spavin was undertaken. The lameness score of the lamest limb was assessed following distal tarsal analgesia of the contralateral limb and followed-up using the same procedure throughout the study. Bone spavin in the lamest limb was confirmed by distal tarsal analgesia and radiography. Horses were treated at Day 0 and reassessed 60 days later after controlled exercise. A second nonblinded treatment was given to unresponsive horses and all horses were re-examined at Day 120. Exercise levels were recorded at each examination.
Results: Eighty-seven horses completed the trial as per the protocol. The tiludronate horses were significantly less lame than the placebo horses (P = 0.0318). Horses treated at Day 60 with tiludronate showed further improvement in lameness at Day 120 (P = 0.0096 and P = 0.0034 for horses treated with tiludronate and placebo at Day 0, respectively). The only significant difference in radiographic findings between tiludronate and placebo was for presence of periarticular osteophytes (P = 0.006).
Conclusions: Tiludronate treatment is proven to be effective in bone spavin in horses in association with a controlled exercise programme.
Clinical relevance: Tiludronate in combination with controlled exercise offers an alternate medical treatment for bone spavin.
64 citations
TL;DR: The efficiency of autologous transplantations of adipose-derived mesenchymal stem cells for equine bone spavin treatment is demonstrated and this research confirms the long-term beneficial influence resulting from stem cell therapy in horse boneSpavin treatment, in contrast to routine steroid usage.
Abstract: In this article we demonstrate the efficiency of autologous transplantations of adipose-derived mesenchymal stem cells for equine bone spavin treatment. Horses qualified to the study were divided into three groups: (i) research – treated with intra-articular injections of autologous stem cells, (ii) comparison treated with steroid drugs and (iii) control – untreated. All animals underwent comprehensive clinical examination before and after treatment. Our research confirms the long-term beneficial influence resulting from stem cell therapy in horse bone spavin treatment, in contrast to routine steroid usage.
57 citations
TL;DR: Radiographic signs of DJD in the distal tarsal joints were found in 30.3% of the horses and the prevalence was strongly correlated with age, while lameness was usually mild and, in most cases, detectable only after the flexion test.
Abstract: Summary
The prevalence of degenerative joint disease (DJD) in the distal tarsal joints and the relation between radiographic and clinical signs compatible with the disease were estimated in a population of Icelandic horses used for riding. The material consisted of 614 horses age 6–12 years (mean age = 7.9 years). Radiographs with 3 projections of each tarsus were made and a clinical examination, including palpation of the medial aspect of the distal tarsus and motion evaluation of the hindlimbs before and after a flexion test of the tarsus, was performed. Radiographic signs of DJD in the distal tarsal joints were found in 30.3% of the horses and the prevalence was strongly correlated with age. Hindlimb lameness before and after flexion test and palpation abnormalities were significantly associated with the radiographic findings. The lameness was usually mild and, in most cases, detectable only after the flexion test. The prevalence of lameness was not significantly correlated with age. Lameness could not be predicted by details of the radiographic findings.
53 citations
TL;DR: During a 3 year period 20 horses with bone spavin were treated by surgical arthrodesis of the affected joints, although one subsequently developed spavin in the other hock and was destroyed.
Abstract: During a 3 year period 20 horses with bone spavin were treated by surgical arthrodesis of the affected joints. The horses chosen for surgery were those with osteoarthritis, but with little or no evidence of periostitis. Whenever possible they were examined periodically during the postoperative period to evaluate the lameness and to assess the progress of ankylosis by radiography. Three of the horses were still lame 12 months later. The remainder returned to normal work, although one subsequently developed spavin in the other hock and was destroyed. The earliest return to soundness was 3 1/2 months, the longest 10 months (average 5 1/2 months).
44 citations
TL;DR: Establishment of the normal prevalence and distribution of radiographic changes in the hocks and stifles of Thoroughbred yearlings in New Zealand will allow comparison with populations of young horses in other countries and assist veterinarians to identify abnormally high or low prevalence on individual farms.
Abstract: AIM: To characterise the prevalence and distribution of radiographic changes in the hocks and stifles of Thoroughbred yearling colts and fillies in New Zealand and compare them with other populations of young horses. METHODS: Repository radiographs taken in New Zealand for the 2003–2006 Thoroughbred national yearling sales were evaluated by two individual readers. The distribution of radiographic changes was classified as left side only, right side only, or bilateral. Lesions were categorised by type, location, and sex of the yearling. Complete sets of hock and stifle radiographs of 1,505 yearlings were evaluated. RESULTS: Osteophytes or enthesophytes were seen radiographically in the distal tarsal joints of 460/1,505 (31%) horses. Osteochondrosis was seen in the tibiotarsal joint of 66/1,505 (4%) horses, and in the femoropatellar joint of 40/1,505 (3%) horses. Radiographic lucency in the distal or axial aspect of the medial femoral condyle was seen in 247/1,505 (16%) horses, and lucencies consis...
38 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2020 | 2 |
| 2018 | 1 |
| 2017 | 3 |
| 2016 | 1 |
| 2015 | 1 |