Topic
Bone Marrow Collection
About: Bone Marrow Collection is a research topic. Over the lifetime, 50 publications have been published within this topic receiving 1128 citations.
Papers
TL;DR: Investigating the prognostic value of quantifying tumor cells in bone marrow and blood by immunocytology in children with high-risk, metastatic neuroblastoma found it provides prognostic information that can identify patients with very high- risk disease who should be considered for experimental therapy that might improve outcome.
Abstract: PURPOSE: This study investigated the prognostic value of quantifying tumor cells in bone marrow and blood by immunocytology in children with high-risk, metastatic neuroblastoma. PATIENTS AND METHODS: Patients with stage IV neuroblastoma (N = 466) registered on Children’s Cancer Group study 3891 received five cycles of induction chemotherapy and were randomized either to myeloablative chemoradiotherapy with autologous purged bone marrow rescue or to nonmyeloablative chemotherapy. Subsequently, they were randomized to 13-cis-retinoic acid or no further treatment. Immunocytologic analyses of bone marrow and blood were performed at diagnosis, week 4, week 12, bone marrow collection, and end induction and were correlated with tumor biology, clinical variables, treatment regimen, and event-free survival (EFS). RESULTS: Immunocytology identified neuroblastoma cells in bone marrow of 81% at diagnosis, 55% at 4 weeks, 27% at 12 weeks, 19% at bone marrow collection, and 14% at end induction. Tumor cells were detect...
157 citations
TL;DR: Washing out bone marrow collection sets may constitute a highly ethical source of MSCs for research purposes and may be utilized also in clinical applications.
59 citations
TL;DR: In a series of 100 bone marrow harvests, the incidence of bacterial contamination of the bone marrow graft was 17 percent as discussed by the authors, and ex vivo manipulation of some of the grafts prior to infusion may have caused additional bacterial contamination.
56 citations
TL;DR: This work shows that when undertaking single sitting procedures, the pelvis remains the optimum source for obtaining MSCs, despite the morbidity associated with bone marrow collection from the Pelvis.
36 citations
Journal Article•
TL;DR: The role of the oncology nurse practitioner in the performance of bone marrow aspiration and biopsy is described and the indications and diagnostic value ofBone marrow examination is discussed.
Abstract: Purpose/objectives To describe the role of the oncology nurse practitioner in the performance of bone marrow aspiration and biopsy and discuss the indications and diagnostic value of bone marrow examination. Data sources Published articles, textbooks, personal experience. Data synthesis Bone marrow examination is useful in the diagnosis of many nonhematologic and hematologic conditions. Having a nurse practitioner perform bone marrow aspiration can improve patient care and comfort. Conclusions Greater understanding of bone marrow aspiration procedure and diagnostic tests helps nurse practitioners and oncology nurses to provide better patient care. Implications for nursing practice Advanced practice nurses in the oncology setting must take an active role in the development and implementation of clinical practice protocols for bone marrow collection.
27 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2020 | 1 |
| 2018 | 1 |
| 2017 | 3 |
| 2016 | 3 |
| 2014 | 4 |