About: Biological interface engineering is a research topic. Over the lifetime, 10 publications have been published within this topic receiving 55 citations.
TL;DR: This issue highlights some applications of organic electronics to bioelectronics, while at the same time bringing to the foreground some important implications for the design of materials and devices.
Abstract: This is a special issue dedicated to the emerging field of organic bioelectronics. Bridging the interface between biology and electronics necessitates advances in materials, which, in turn, enable better performing devices or entirely new device concepts. Existing bioelectronic devices utilize conventional materials, such as metals, that are not intrinsically compatible with biological systems and do not efficiently convert ionic signals in the biological environment to/from electronic signals. The structural and functional similarity of organic materials to biological ones suggests many applications of the former to neural interfaces, drug delivery, tissue engineering, diagnostics, etc. This interdisciplinary effort has rapidly grown over the last few years with the development of devices that take advantage of the unique features of organics including: (1) their “soft” mechanical properties that mimic those of biological structures; (2) their mixed electronic/ionic conductivity that promotes efficient signal transduction; (3) their transparency that allows the simultaneous use of optical analysis techniques; (4) their facile functionalization by proteins and biomolecules to tune biological properties; and (5) their cost-effective synthesis on a variety of scales.
This issue highlights some applications of organic electronics to bioelectronics, while at the same time bringing to the foreground some important implications for the design of materials and devices. Papers include applications in neural prosthesis, diagnostics based on flexible substrates, devices and circuits based on biomolecules, as well as some fundamental properties and new materials for the biotic/abiotic interface. We hope that you will enjoy reading this issue, whether you are a newcomer to the field or a seasoned veteran!
TL;DR: Sometimes, sub-disciplines within BME are classified by their association(s) with other more established engineering fields, which can include: biochemical-BME, based on Chemical engineering -often associated with biochemical, cellular, molecular and tissue engineering, biomaterials, and biotransport.
Abstract: Biomedical engineering is the application of engineering principles and design concepts to medicine and biology for healthcare purposes. This field seeks to close the gap between engineering and medicine: It combines the design and problem solving skills of engineering with medical and biological sciences to advance healthcare treatment, including diagnosis, monitoring, and therapy. Much of the work in biomedical engineering consists of research and development, spanning a broad array of subfields. Prominent biomedical engineering applications include the development of biocompatible prostheses, various diagnostic and therapeutic medical devices ranging from clinical equipment to micro-implants, common imaging equipment such as MRIs and EEGs, regenerative tissue growth, pharmaceutical drugs and therapeutic biological. But more often, sub-disciplines within BME are classified by their association(s) with other more established engineering fields, which can include:Biochemical-BME, based on Chemical engineering -often associated with biochemical, cellular, molecular and tissue engineering, biomaterials, and biotransport.Bioelectrical-BME, based on Electrical engineering and Computer Science -often associated with bioelectrical and neural engineering, bioinstrumentation, biomedical imaging, and medical devices. This also tends to encompass optics and optical engineering -biomedical optics, bioinformatics, imaging and related medical devices.Biomechanical-BME, based on Mechanical engineering -often associated with biomechanics, biotransport, medical devices, and modeling of biological systems, like soft tissue mechanics.
TL;DR: This paper reviews some recent developments in this solid-state electronic and biological systems interface.
Abstract: Solid-state electronic devices can be engineered to detect and manipulate biological molecules and cells by using electric or magnetic interactions. The integrated circuits, which can contain a large number of such devices, may then potentially be developed into low-cost chip-scale platforms to perform bioanalytical tasks in a multiplexed manner for applications in biology, biotechnology, and personalized medicine. This paper reviews some recent developments in this solid-state electronic and biological systems interface.