Bioceramic

Abstract: Contents Metallic Biomaterials, J.B. Park and Y.K. Kim Stainless Steels * CoCr Alloys * Ti Alloys * Dental Metals * Other Metals * Corrosion of Metallic Implants * Manufacturing of Implants Ceramic Biomaterials, W.G. Billotte Nonabsorbable or Relatively Bioinert Bioceramics * Biodegradable or Resorbable Ceramics * Bioactive or Surface-Reactive Ceramics * Deterioration of Ceramics * Bioceramic Manufacturing Techniques Polymeric Biomaterials, H.B. Lee, G. Khang, and J.H. Lee Polymerization and Basic Structure * Polymers Used as Biomaterials * Sterilization * Surface Modifications for Improving Biocompatability * Chemogradient Surfaces for Cell and Protein Interaction Composite Biomaterials, R. Lakes Structure * Bounds on Properties * Anisotropy of Composites * Particulate Composites * Fibrous Composites * Porous Materials * Biocompatibility Biodegradable Polymeric Biomaterials: An Updated Overview, C.-C. Chu Glycolide/Lactide Based Biodegradable Linear Aliphatic Polyesters * Non-Glycolide/Lactide Based Linear Aliphatic Polyesters * Non-Alphatic Polyesters Type Biodegradable Polymers * Biodegradation Properties of Synthetic Biodegradable Polymers * The Role of Linear Aliphatic Biodegradable Polyesters in Tissue Engineering and Regeneration Biologic Biomaterials: Tissue-Derived Biomaterials (Collagen), S.-T. Li Structure and Properties of Collagen and Collagen-Rich Tissues * Biotechnology of Collagen * Design of a Resorbable Collagen-Based Medical Implant * Tissue Engineering for Tissue and Organ Regeneration Soft Tissue Replacements, K.B. Chandran, K.J.L. Burg, and S.W. Shalaby Blood-Interfacing Implants * Non-Blood-Interfacing Implants for Soft Tissues Hard Tissue Replacements, S-H. Park, A. Llinas, V.K. Goel, and J.C. Keller Bone Repair and Joint Implants * Dental Implants: The Relationship of Materials Characteristics to Biologic Properties Preservation Techniques for Biomaterials, R. Coger and M. Toner Phase Behavior * Nonfreezing Storage: Hypothermic * Freeze-Thaw Technology * Freeze-Drying * Vitrification * Summary Hip Joint Prosthesis Fixation-Problems and Possible Solutions, J.B. Park Acetabular Cup * Femoral Stem * Articulating Surface of the Acetabular Cup and Femoral Head

Abstract: Research on biomaterials has been growing in the last few years due to the clinical needs in organs and tissues replacement and regeneration. In addition, cancer nanomedicine has recently appeared as an effective means to combine nanotechnology developments towards a clinical application. Ceramic materials are suitable candidates to be used in the manufacturing of bone-like scaffolds. Bioceramic materials may also be designed to deliver biologically active substances aimed at repairing, maintaining, restoring or improving the function of organs and tissues in the organism. Several materials such as calcium phosphates, glasses and glass ceramics able to load and subsequently release in a controlled fashion drugs, hormones, growth factors, peptides or nucleic acids have been developed. In particular, to prevent post surgical infections bioceramics may be surface modified and loaded with certain antibiotics, thus preventing the formation of bacterial biofilms. Remarkably, mesoporous bioactive glasses have shown excellent characteristics as drug carrying bone regeneration materials. These bioceramics are not only osteoconductive and osteoproductive, but also osteoinductive, and have therefore been proposed as ideal components for the fabrication of scaffolds for bone tissue engineering. A recent promising development of bioceramic materials is related to the design of magnetic mediators against tumors. Magnetic composites are suitable thermoseeds for cancer treatment by hyperthermia. Moreover, magnetic nanomaterials offer a wide range of possibilities for diagnosis and therapy. These nanoparticles may be conjugated with therapeutic agents and heat the surrounding tissue under the action of alternating magnetic fields, enabling hyperthermia of cancer as an effective adjunct to chemotherapy regimens.