TL;DR: In this article, a recombinant batroxobin mixture, a hemostatic composition comprising the same, and a method for preparing the same is presented, which can be easily used by being applied as a topical hemostastic agent.
Abstract: The present invention relates to a novel recombinant batroxobin mixture, a hemostatic composition comprising the same, and a method for preparing the same. According to the present invention, the hemostatic composition of the present invention has an excellent hemostatic effect by suppressing rebleeding, and maintains activity thereof even when prepared in a solid form, and thus, the composition of the present invention can be easily used by being applied as a topical hemostatic agent.
TL;DR: Wang et al. as mentioned in this paper provided a method for fermenting traditional Chinese medicine with batroxobin yeast, and the method can effectively improve a medicinal material use rate and enhance the medicinal effect.
Abstract: The invention belongs to the field of traditional Chinese medicine, and aims to provide a method for fermenting traditional Chinese medicine with batroxobin yeast. The method can effectively improve a medicinal material use rate and enhance the medicinal effect. For realizing the purposes, an adopted technical solution comprises: placing prepared medicinal materials for external application into a container, adding water for cooking for 3-5h, then naturally cooling to 28-36 DEG C, adding batroxobin and yeast, and preserving temperature and fermenting for 1-3h, wherein a ratio of the batroxobin to the medicinal materials is 500-1000BU to 100g, a ratio of the yeast to the medicinal materials is 2-3g to 100g. The batroxobin can effectively dissolve fibers in the traditional Chinese herbal medicines, cause effective components wrapped in the fibers in the medicinal materials to be released, improve the effective medicinal material use rate and enhance the medicinal effect. The batroxobin has the effects of reducing blood viscosity, dissolving fibrinogen, inhibiting thrombogenesis and dissolving thrombus, and can promote blood of a human body to flow and improve the absorbing ability of the human body to the medicine.
TL;DR: In this article, a recombinant batroxobin mixture, a hemostatic composition comprising the same, and a method for preparing the same is described, and the present composition can be easily used by being applied as a topical hemostastic agent.
Abstract: The present invention relates to a novel recombinant batroxobin mixture, a hemostatic composition comprising the same, and a method for preparing the same According to the present invention, the hemostatic composition of the present invention has an excellent hemostatic effect by suppressing rebleeding, and maintains activity thereof even when prepared in a solid form, and thus, the composition of the present invention can be easily used by being applied as a topical hemostatic agent