Topic
Atractylodes
About: Atractylodes is a research topic. Over the lifetime, 3417 publications have been published within this topic receiving 10796 citations.
Papers published on a yearly basis
Papers
TL;DR: In vivo experiments showed that the five components exhibited significant inhibiting effects both on the ear edema induced by xylene and on the peritoneal capillary permeability induced by acetic acid in mice.
102 citations
TL;DR: Atractylon significantly inhibited NO and prostaglandin E2 production as well as inducible NO synthase and cyclooxygenase-2 expression in LPS-induced RAW 264.7 cells, and can be used as a bioactivity marker in A. japonica.
Abstract: The rhizomes of many Atractylodes species, including Atractylodes chinensis Koidzumi, Atractylodes macrocephala Koidzumi, and Atractylodes japonica Koidzumi, are collectively termed Atractylodis Rhizoma. We prepared n-hexane extracts of the three species and evaluated their anti-inflammatory effects on lipopolysaccharide (LPS)-induced RAW 264.7 cells. Among all n-hexane extracts, those of A. japonica most strongly inhibited nitric oxide (NO) production in LPS-induced RAW 264.7 cells; five sesquiterpenes, atractylon, atractylenolide I, atractylenolide II, atractylenolide III, and 8-epiasterolid, were isolated from A. japonica. The phytochemical content of A. japonica was similar to those of A. chinensis and A. macrocephala. Moreover, the atractylon concentration was higher in A. japonica than in A. chinensis and A. macrocephala. Atractylon significantly inhibited NO and prostaglandin E2 production as well as inducible NO synthase and cyclooxygenase-2 expression in LPS-induced RAW 264.7 cells. Atractylon (40 mg/kg) also significantly reduced the acetic-acid-induced writhing response, carrageenan-induced paw edema, and hot-plate latent pain response in mice. According to the results, A. japonica has anti-inflammatory and antinociceptive effects and atractylon is the major active component of A. japonica. Therefore, atractylon can be used as a bioactivity marker in A. japonica.
88 citations
86 citations
TL;DR: The in vitro antitumor activity of ACPS-1 was evaluated on four human cancer cell lines and showed that it could significantly inhibit Hela, HepG2, and 7721 cell proliferation, especially HepG 2, for which the fructan showed a proliferative inhibition rate as high as 87.40%.
84 citations
Patent•
31 Oct 2012
TL;DR: Wang et al. as mentioned in this paper revealed a Chinese herbal livestock feed additive and the application thereof, belonging to the technical field of preparation of livestock farming feed, which has prominent substantive features and significant advantages of capability of improving disease resistance and disease prevention, no hormone, no toxic side effect, and delicious, safe, reliable, healthy and green livestock meat.
Abstract: The invention discloses a Chinese herbal livestock feed additive and the application thereof, belonging to the technical field of preparation of livestock farming feed. The Chinese herbal livestock feed additive is powder prepared from hawthorn, medicated leaven, fried malt, yam, barley, licorice, Chinese angelica, astragalus, Codonopsis, lily, Ophiopogon, Atractylodes lancea, bighead atractylodes rhizome, betel nut, Cyrtomium fortunei, Agrimonia pilosa, cortex acanthopanacis, Curculigo, Citrus aurantium, basil, mugwort, garlic powder, onion powder, Elsholtzia grass, semen cassiae, mustard Seed, Ligustrum lucidum, rangooncreeper Fruit, radish seed, psoralen, dodder and other Chinese herbs according to the conventional preparation technology. Compared with the prior art, the Chinese herbal livestock feed additive has prominent substantive features and significant advantages of capability of improving disease resistance and disease prevention, no hormone, no toxic side effect, and delicious, safe, reliable, healthy and green livestock meat.
84 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 23 |
| 2024 | 23 |
| 2023 | 27 |
| 2022 | 39 |
| 2021 | 13 |
| 2020 | 38 |