TL;DR: These preliminary observations suggest that elective, nonsurgical insertion of an endovascular stent-graft is safe and efficacious in selected patients who have thoracic aortic dissection and for whom surgery is indicated.
Abstract: Background The treatment of thoracic aortic dissection is guided by prognostic and anatomical information. Proximal dissection requires surgery, but the appropriate treatment of distal thoracic aortic dissection has not been determined, because surgery has failed to improve the prognosis. Methods We prospectively evaluated the safety and efficacy of elective transluminal endovascular stent–graft insertion in 12 consecutive patients with descending (type B) aortic dissection and compared the results with surgery in 12 matched controls. In all 24 patients, aortic dissection was diagnosed by magnetic resonance angiography. In each group, the dissection involved the aortic arch in 3 patients and the descending thoracic aorta in all 12 patients. With the patient under general anesthesia, either surgical resection was undertaken or a custom-designed endovascular stent–graft was placed by unilateral arteriotomy. Results Stent–graft placement resulted in no morbidity or mortality, whereas surgery for type B disse...
TL;DR: With further refinement, endoluminal repair may emerge as an interventional strategy to treat infrarenal aortic aneurysms, especially in patients at high surgical risk.
Abstract: Background The treatment of aortic aneurysms with endovascular stents or stent–graft prostheses is receiving increasing attention as an alternative to major abdominal surgery. To define the clinical value of this technique, we prospectively studied the use of stent–graft endoprostheses made of nitinol and covered with polyester fabric for the treatment of infrarenal abdominal aortic aneurysms. Methods We treated a total of 154 patients at three academic hospitals. Twenty-one patients with aortic aneurysms not involving the aortic bifurcation received straight stent–grafts, and 133 patients with aortic aneurysms involving the bifurcation and the common iliac arteries received bifurcated stent–grafts. After a unilateral surgical arteriotomy, the endoprostheses were advanced through the femoral arteries and placed under fluoroscopic guidance. Computed tomography and intraarterial angiography were performed during an average follow-up of 12.5 months. Results The primary success rate, defined as complete exclu...
TL;DR: The potential feasibility of grafting the internal thoracic artery to coronary arteries with the heart arrested and protected, without a major thoracotomy or sternotomy is demonstrated.
TL;DR: In this article, a shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed, which includes a first tubular member (10) having a proximal end adapted to receive blood from a first region of an artery, a distal end is adapted to release blood into a second region of the artery.
Abstract: A shunt and method of use for maintaining distal blood flow during an arteriotomy procedure is disclosed. The shunt includes a first tubular member (10) having a proximal end adapted to receive blood from a first region of an artery. A distal end is adapted to release blood into a second region of the artery. The shunt includes a second tubular member (14) having a lumen which either merges and communicates at its distal end with a lumen of the first tubular member, or rides separate and parallel to it. The shunt is secured to the lumen of the artery. A blood filter device (41, 42) is deployed within the artery. The proximal opening of the shunt is inserted into the first region of the artery, and secured to the lumen of the artery. Endarterectomy is performed on the artery and embolic material dislodged during the procedure is captured by the filter.
TL;DR: In this article, the arteriotomy site can be sealed by delivery of a suitable sealant such as a patient specific autologous fibrin glue to a debrided, synthesized area adjacent to the extravascular opening.
Abstract: The present invention provides an apparatus (10) and a method for quickly and effectively sealing an arteriotomy site in a patient. In particular, the invention provides an apparatus and method for sealing an arteriotomy site which can be performed by a single operator. The arteriotomy can be sealed by delivery of a suitable sealant (36) such as a patient specific autologous fibrin glue to a debrided, synthesized area (35) adjacent to the extravascular opening (4) of the arteriotomy. Alternatively, synthetically produced fibrin glue or other sealants can be utilized in a method of sealing an arteriotomy site.