Showing papers on "Apitherapy published in 2011"
TL;DR: Hepatotoxicity is described in a 35-year-old female, following bee sting therapy for multiple sclerosis, presented to the clinic 3 wk after therapy with a history of progressive jaundice, and has been attending the clinic now for the last 9 mo.
Abstract: The use of bee venom as a therapeutic agent for the relief of joint pains dates back to Hippocrates, and references to the treatment can be found in ancient Egyptian and Greek medical writings as well. Also known as apitherapy, the technique is widely used in Eastern Europe, Asia, and South America. The beneficial effects of bee stings can be attributed to mellitinin, an anti-inflammatory agent, known to be hundred times stronger than cortisone. Unfortunately, certain substances in the bee venom trigger allergic reactions which can be life threatening in a sensitized individual. Multiple stings are known to cause hemolysis, kidney injury, hepatotoxicity and myocardial infarction. The toxicity can be immediate or can manifest itself only weeks after the exposure. We describe hepatotoxicity in a 35-year-old female, following bee sting therapy for multiple sclerosis. She presented to our clinic 3 wk after therapy with a history of progressive jaundice. The patient subsequently improved, and has been attending our clinic now for the last 9 mo.
29 citations
Journal Article•
TL;DR: Newly formulated ointment containing 20% active antimicrobial honey is very effective and alternative low-cost product for the treatment of wound infections.
Abstract: Background: Honey is a gift of nature, principally identified and valued to possess antimicrobial and anti-inflammatory activity and has been used as a natural remedy of wounds since ancient times. The objectives of this study were to evaluate the antimicrobial activity of honey against micro-organisms, to formulate a honey ointment and to evaluate the efficacy of such ointment by conducting clinical trials on skin wound infection. Methods: This experimental study was conducted at Department of Pharmaceutics, Faculty of Pharmacy, University of Karachi and Out-patient Department of Dermatology, Fauji Foundation Hospital, Rawalpindi from November 2009 to October 2010. The antimicrobial activity of Pakistani floral sources ( Trachysperm copticum , Acacia nilotica species indica , Zizyphus ) honey samples was investigated by disc diffusion method against freshly isolated wound infecting bacteria ( Staphylococci aureus, Staphylococci epidermidis, Streptococcus faecalis , Pseudomonas aeruginosa, Klebsiella pneumonia, Escherichia coli, Proteus vulgaris and Candida albicans ), and Staphylococci aureus ATCC 6538, Pseudomonas aeruginosa ATCC 9022, Escherichia coli ATCC 25922 , Candida albican ATCC 15146. An ointment containing 20% active antimicrobial honey was formulated. The efficacy of such ointment was evaluated by passing thought clinical trials. A total number of 27 patients (23 skin wound infection, and 4 diabetic foot ulcer) were involved in the study. Thin layer of newly formulated honey ointment on gauze were applied two to three times per day till complete healing. Results: In microbiological assay the honey samples were found to exhibit a very promising antimicrobial activity against all the micro-organisms tested. In clinical trial very significant results (99.15%) healing was observed in skin wound infections cases with mean healing time of 5.86 (2–20) days, and 95% diabetic foot ulcers healed with the mean healing time of 20 (8–40) days. Conclusion: Newly formulated ointment containing 20% active antimicrobial honey is very effective and alternative low-cost product for the treatment of wound infections. Keyword: antimicrobial activity , honey ointment , wound infection , diabetic foot ulcer
11 citations
31 Oct 2011-Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine
TL;DR: The administration of apitherapy diet is indicated in chronic liver affection with the improvement of platelet parameters with the increase of number of thrombocytes, mean platelet volume and platelet distribution width.
Abstract: The present experiment evaluates the influence of apitherapy diet on CCl4 experimentally induced liver disease in Wistar rats, by the means of number of thrombocytes, mean platelet volume and platelet distribution width. Protection was achieved by the administration of apitherapy products for three weeks. Hepatic lesion was induced by intraperitoneal injection of CCl4 (dissolved in paraffin oil, 10% solution). The experiment was unfolded on 60 Wistar rats, divided into 6 groups: control group standard food (group I), control group apitherapy diet (group II), control group apitherapy diet + royal jelly (group III), CCl4 group (group IV), group CCl4 + apitherapy diet (group V), group CCl4 + apitherapy diet + royal jelly (group VI). In comparison with group IV, the administration of apitherapy diet (group V) reveals the increase of number of thrombocytes (765.7 61.07 versus 918.3 63.59), the decrease of the mean platelet volume (8.32 0.69 versus 7.1 0.65) and the decrease of platelet distribution width (9.31 1.13 versus 7.14 0.7). The administration of apitherapy diet and royal jelly (group VI) determines, when compared to CCl4 group: the increase of number of thrombocytes (765.7 61.07 versus 930.4 7.16), the decrease of the mean platelet volume (8.32 0.69 versus 6.74 0.12) and the decrease of platelet distribution width (9.31 1.13 versus 6.71 0.15). The administration of apitherapy diet is indicated in chronic liver affection with the improvement of platelet parameters.
1 Jan 2011
TL;DR: In this article, the influence of apitherapy diet on CCl4 induced hepatopathy in laboratory animals, by the means of leukocyte formula, was evaluated by using an automatic analyzer and commercial kits.
Abstract: The purpose of this experiment is to evaluate the influence of apitherapy diet on CCl4 induced hepatopathy in laboratory animals, by the means of leukocyte formula. The experiment was unfolded on six groups of Wistar rats: control group standard food (group I), control group apitherapy diet (group II), control group apitherapy diet + royal jelly (group III), CCl4 group (group IV), group CCl4 + apitherapy diet (group V), group CCl4 + apitherapy diet + royal jelly (group VI). The animals were handled under general anesthesia with thiopental. Hepatic lesion was induced by intraperitoneal injection of CCl4 (dissolved in paraffin oil, 10% solution). Hepatoprotection was achieved with apitherapy products (Apiregya, ApiImunomod, ApiImunostim, ApiImunostim Forte). Determination of the leukocyte formula was achieved by using an automatic analyzer and commercial kits. Administration of apitherapy diet and respectively of apitherapy diet and royal jelly in laboratory animals with CCl4 induced hepatopathy improves the values of parameters from the leukocyte formula when compared with CCl4 group.
31 Oct 2011-Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Veterinary Medicine
TL;DR: Administration of apitherapy diet and respectively of ApiImunomod and royal jelly in laboratory animals with CCl4 induced hepatopathy improves the values of parameters from the leukocyte formula when compared with C Cl4 group.
Abstract: The purpose of this experiment is to evaluate the influence of apitherapy diet on CCl4 induced hepatopathy in laboratory animals, by the means of leukocyte formula. The experiment was unfolded on six groups of Wistar rats: control group standard food (group I), control group apitherapy diet (group II), control group apitherapy diet + royal jelly (group III), CCl4 group (group IV), group CCl4 + apitherapy diet (group V), group CCl4 + apitherapy diet + royal jelly (group VI). The animals were handled under general anesthesia with thiopental. Hepatic lesion was induced by intraperitoneal injection of CCl4 (dissolved in paraffin oil, 10% solution). Hepatoprotection was achieved with apitherapy products (Apiregya, ApiImunomod, ApiImunostim, ApiImunostim Forte). Determination of the leukocyte formula was achieved by using an automatic analyzer and commercial kits. Administration of apitherapy diet and respectively of apitherapy diet and royal jelly in laboratory animals with CCl4 induced hepatopathy improves the values of parameters from the leukocyte formula when compared with CCl4 group.
1 May 2011
TL;DR: This piece of writing throws a light on proplis and its clinical importance in medicine and dentistry and points towards the paradigm shift from costlier antibiotic therapies to the old tradition remedies with minimum side effects like apitherapy.
Abstract: “Look back into the nature and then you will understand everything better.” This quote by Albert Einstein clearly point towards the paradigm shift from costlier antibiotic therapies to the old tradition remedies with minimum side effects like apitherapy. Apitherapy is the medicinal use of products made by honeybees. Therapies involving the honeybee have existed for thousands of years and some may be as old as human medicine itself. This can include the use of honey, propolis, pollen, royal jelly, and bee venom. This piece of writing throws a light on proplis and its clinical importance in medicine and dentistry. Key Words: Apitherapy, Propolis, Phytotherapy, Plant. Introduction: Apitherapy, or ―bee therapy‖ is the medicinal use of products made by honeybees. Bees have been in existence for 125 million years and their evolutionary success has allowed them to become perennial species that can exploit virtually all habitats on Earth. This success is largely because of the chemistry and application of the specific products that bees manufacture: honey, beeswax, venom, propolis, pollen and royal jelly