TL;DR: Rapid, on‐site HIV testing was feasible, preferred by clients, and resulted in significant improvement in the number of persons learning their serostatus, without increasing the costs or decreasing the effectiveness of counseling and testing.
Abstract: Background New rapid HIV antibody tests have allowed provision of results and result-specific counseling on the day on initial visit, and have the potential to increase the efficiency of HIV counseling and testing. Methods To evaluate the use of rapid testing with same-day results in public clinics, the Single Use Diagnostic System HIV-1 rapid assay was used for a 3-month period at an anonymous testing clinic and a sexually transmitted disease (STD) clinic in Dallas, Texas. Non-reactive rapid test results were reported as HIV-negative. Reactive results were reported as 'preliminary positive'. These procedures were compared with standard testing during a baseline period, with respect to number of clients receiving results and post-test counseling, client satisfaction, counselor acceptance, cost and effectiveness at reducing HIV risk. Results Rapid testing resulted in an increase in the number of persons learning their serostatus: a 4% increase for uninfected and a 16% increase for infected clients at the Anonymous Testing Clinic; a 210% increase for uninfected patients and a 23% increase for infected patients at the STD clinic. Rapid testing resulted in a cost saving of US$ 11 per test in both the anonymous and STD clinics. Of those previously tested, 88% responded that they preferred the rapid test. In the year following initial HIV test, clients tested with rapid and standard procedures were equally likely to return to the clinic with a new STD (odds ratio, 0.97; 95% confidence interval, 0.7-1.4). Conclusions Rapid, on-site HIV testing was feasible, preferred by clients, and, resulted in significant improvement in the number of persons learning their serostatus, without increasing the costs or decreasing the effectiveness of counseling and testing.
TL;DR: People tested anonymously sought testing and medical care earlier in the course of HIV disease than did persons tested confidentially, and anonymous testing remained significantly associated with earlier entry into medical care.
Abstract: Context.—Infection with the human immunodeficiency virus (HIV) is the only infectious
disease for which anonymous testing is publicly funded, an exception that
has been controversial.Objective.—To assess whether anonymous HIV testing was associated with earlier
HIV testing and HIV-related medical care than confidential HIV testing.Design.—Retrospective cohort.Setting.—Arizona, Colorado, Missouri, New Mexico, North Carolina, Oregon, and
Texas.Participants.—Probability sample of 835 new acquired immunodeficiency syndrome (AIDS)
cases reported to the state health department's HIV/AIDS Reporting System
from May 1995 through December 1996. All had responded to the AIDS Patient
Survey; 643 had been tested confidentially for HIV, and 192 had been tested
anonymously.Main Outcome Measures.—First CD4+ cell count; number of days from HIV-positive test
result to first HIV-related medical care, from first HIV-related medical care
to AIDS, and from first HIV-positive test result to AIDS.Results.—Persons tested anonymously sought testing and medical care earlier in
the course of HIV disease than did persons tested confidentially. Mean first
CD4+ cell count was 0.427×109/L in persons tested
anonymously vs 0.267×109/L in persons tested confidentially.
Persons tested anonymously experienced an average of 918 days in HIV-related
medical care before an AIDS diagnosis vs 531 days for persons tested confidentially.
The mean time from learning they were HIV positive to the diagnosis of AIDS
was 1246 days for persons tested anonymously vs 718 days for persons tested
confidentially. After adjustment for the subject's age, sex, race/ethnicity,
education, income, insurance status, HIV exposure group, whether the respondent
had a regular source of care or symptoms at the time of the HIV test, and
state residence, anonymous testing remained significantly associated with
earlier entry into medical care (P<.001).Conclusion.—Anonymous testing contributes to early HIV testing and medical care.
TL;DR: This pilot study established that unlinked anonymous testing of dried blood spots routinely collected on Guthrie cards for neonatal screening is a feasible method for monitoring HIV prevalence in women at the time of delivery.
TL;DR: Dried blood spot samples from newborn babies have been successfully tested for HIV-1 antibody by the particle agglutination method to assess the prevalence of infection in the mothers and identified as HIV-positive all babies known to be so in named testing programmes.
TL;DR: Results indicate that genetic counselors have limited patient experiences with direct-to-consumer genetic testing and are cautiously considering if and under what circumstances this approach should be used.