Topic
Anoectochilus
About: Anoectochilus is a research topic. Over the lifetime, 116 publications have been published within this topic receiving 634 citations.
Papers published on a yearly basis
Papers
TL;DR: In an in vitro study, the LD50 values for H2O2‐induced cytotoxicity in BALB/c normal liver cells were significantly higher after kinsenoside pretreatment than after vehicle alone, further confirming that kinsenosides shows significant antihepatotoxic activity.
Abstract: Carbon tetrachloride (CCl(4)) causes chronic hepatitis, featuring an increase in hepatic hydroxyproline, spleen weight and serum GPT levels and a decrease in plasma albumin levels. Crude extracts of fresh whole plants of Anoectochilus formosanus showed inhibition of chronic hepatitis induced by CCl(4) in mice. Bioactivity-guided fractionation and spectroscopic analysis revealed that kinsenoside was the most active compound. In an in vitro study, the LD(50) values for H(2)O(2)-induced cytotoxicity in BALB/c normal liver cells were significantly higher after kinsenoside pretreatment than after vehicle alone, further confirming that kinsenoside shows significant antihepatotoxic activity.
64 citations
TL;DR: 1 suppressed the body and liver weight increase, significantly ameliorated the triglyceride level in the liver, and also reduced the deposition of uterine fat-pads in aurothioglucose-induced obese mouse.
Abstract: A higher concentration of kinsenoside, 3-(R)-3-β-D-glucopyranosyloxybutanolide (1), was detected in the crude drug Anoectochilus formosanus, and A. koshunensis by HPLC analysis. A methylation reaction occurred to give methyl ester (4) when the lactone ring of 1 was cleaved by silica gel catalysis using methanol containing solvent used in the purification step resulting in difficulty to purify 1. To avoid the cleavage reaction, a reversed-phase or silica gel column without methanol was used to give a high yield of 1. In an anti-hyperliposis assay using high-fat diet rats, 1 significantly reduced the weights of body and liver, and also decreased the triglyceride level in the liver compared to those of control rats. On the other hand, the epimer of 1, 3-(S)-3-β-D-glucopyranosyloxybutanolide (2), trivially named goodyeroside A, which was isolated from Goodyera species, had no effect for anti-hyperliposis. In aurothioglucose-induced obese mouse, 1 suppressed the body and liver weight increase, significantly ameliorated the triglyceride level in the liver, and also reduced the deposition of uterine fat-pads.
53 citations
TL;DR: In this paper, a simple aliphatic glucoside, 3-(R)-3-β-d -glucopyranosyloxybutanolide (kinsenoside) with its congeners and a heterocyclic aromatic glucosides, β- d -glocopyranoyl-3 pyridinemethanol (nicoloside) have been isolated from whole Anoectochilus koshunensis plants.
43 citations
1 Jan 1993
TL;DR: In this article, a simple aliphatic glucoside, 3-(R)-3-β-d -glucopyranosyloxybutanolide (kinsenoside) with its congeners and a heterocyclic aromatic glucosides, β- d -glocopyranoyl-3 pyridinemethanol (nicoloside) have been isolated from whole Anoectochilus koshunensis plants.
Abstract: Abstract A new simple aliphatic glucoside, 3-(R)-3-β- d -glucopyranosyloxybutanolide (kinsenoside) with its congeners and a heterocyclic aromatic glucoside, β- d -glucopyranosyl-3-pyridinemethanol (nicoloside) have been isolated from whole Anoectochilus koshunensis plants. Their structures were elucidated from chemical and spectroscopic evidence.
36 citations
TL;DR: Investigating the effects and potential mechanism of inoculation with two Bacillus velezensis strains on the growth and quality improvement of Anoectochilus roxburghii indicated the increase of abundance of beneficial microorganisms, such as nitrogen-fixing bacteria, Basidiomycota and Ascomycota both of which are known to fuel their plant partners with mineral nutrients from the soil.
32 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2020 | 6 |
| 2019 | 7 |
| 2018 | 9 |
| 2017 | 13 |
| 2016 | 9 |