Topic
Androstanolone
About: Androstanolone is a research topic. Over the lifetime, 69 publications have been published within this topic receiving 1925 citations. The topic is also known as: stanolone & dihydrotestosterone.
Papers published on a yearly basis
Papers
TL;DR: Methyltrienolone (R 1881), 17beta-hydroxy-17alpha-methyl-estra-4,9,11-trien-3-one, a very active androgen, binds specifically to rat prostate cytosol with a higher affinity than androstanolone, and is thus a useful tool for the detection of elusive androgen receptors and for their study in human tumors where interference from plasma contamination has to be circumvented.
216 citations
TL;DR: By exchanging bound endogenous hormone in rat prostate cytosol with labelled R 1881, it is possible to measure total (free anc occupied) binding sites in androgen receptor sites in human benign prostatic hypertrophy.
201 citations
TL;DR: A prostatic cytosol receptor of high affinity for androstanolone, a major metabolite of testosterone in the prostate, displays interconvertibility of the heavy “8–9 S’ and light “KCl-5 S” conformations, and binds potent “anti-androgens” .
184 citations
TL;DR: Androstanolone was more active than testosterone and also provoked epithelial hyperplasia which was seen only after high doses of testosterone, indicating that testosterone action may be related to its conversion to different active metabolites, and particularly to androStanolone and 3β-androstanediol.
138 citations
TL;DR: The ability to transform testosterone into DHT is much higher in all structures examined (with the exception of the prostate) in prepuberal than in adult rats.
138 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 2 |
| 2018 | 1 |
| 2014 | 1 |
| 2013 | 1 |
| 2012 | 2 |
| 2011 | 2 |