TL;DR: This paper achieves accurate spatial locations of the radioactive seeds in an interstitial implant by using three radiographs whose x-ray source positions are in a plane which does not intersect the implant and widely separated to achieve adequate parallax.
Abstract: The three-dimensional (3-D) locations of the radioactive seeds in an interstitial implant can be obtained from stereo-shift or orthogonal radiographs. When an implant contains a large number of seeds, however, there are often ambiguities in identifying corresponding seed images on two radiographs. The authors' method achieves accurate spatial locations by using three radiographs whose X-ray source positions are (i) in a plane which does not intersect the implant and (ii) widely separated to achieve adequate parallax. All triangulation is done in an anatomical coordinate reference frame attached to the patient so that patient motion does not introduce errors. The authors achieve independent error-insensitive calibration of each radiograph, rapid and accurate data entry in the local coordinates of each radiograph, 3-D seed location in the patient (anatomical) reference frame, and automatic verification of each calculation.
TL;DR: The problem of medical image registration as concerns human brain images is addressed in this thesis and specific chapters include a survey of recent literature, CT/MR registration using mathematical image features (edges and ridges), monomodal SPECT registration, and CT/ MR/SPECT/PET registration using image features extracted by the use of mathematical morphology.
Abstract: In modern clinical practice, the clinician can make use of a vast array of specialized imaging techniques supporting diagnosis and treatment. For various reasons, the same anatomy of one patient is sometimes imaged more than once, either using the
same imaging apparatus (monomodal acquisition ), or different ones (multimodal acquisition). To make simultaneous use of the
acquired images, it is often necessary to bring these images in registration, i.e., to align their anatomical coordinate systems.
The problem of medical image registration as concerns human brain images is addressed in this thesis. The specific chapters
include a survey of recent literature, CT/MR registration using mathematical image features (edges and ridges), monomodal
SPECT registration, and CT/MR/SPECT/PET registration using image features extracted by the use of mathematical
morphology.
TL;DR: An ultrasound-based approach is proposed that exploits prior knowledge about the anatomy of the pelvis in the form of a 3D surface atlas that was able to localize the anatomical coordinate system with the accuracy of about 1 degree.
Abstract: In Total Hip Replacement (THR) procedures, misalignment of the acetabular component can lead to dislocation and impingement. For the successful alignment of acetabular component, precise estimation of pelvic anatomical coordinate system is necessary. Conventional navigation systems use CT scan or fluoroscopy, or involve implanted bone fiducials or invasive probing of bony landmarks to locate the anatomical coordinate. In this paper, an ultrasound-based approach is proposed that exploits prior knowledge about the anatomy of the pelvis in the form of a 3D surface atlas. Tracked ultrasound images are utilized to extract sample points from the surface of the pelvis. A generic coordinate system in the specific patient is localized by registering these points to a statistical atlas of the pelvis in which a canonical anatomical coordinate system had been defined. This technique has been evaluated using simulation, dry bone, and cadaver experiments and was able to localize the anatomical coordinate system with the accuracy of about 1 degree.
TL;DR: Both intrinsic and extrinsic methods for studying anatomical coordinates in order to perform statistical inference on random physiological signals F across clinical populations show that the left cingulate gyrus tends to become thinner in schizophrenia relative to the healthy control population.
TL;DR: In this paper, the authors present a system for computer assisted joint replacement surgery, which consists of a sensor for coupling to a first bone to receive positional signals; a beacon for providing the positional signals to the sensor, the object comprising one of a second bone and a surgical tool; a patient-specific jig (PSJ) for guiding a relative position of the sensor and the first bone during coupling to position the sensor in a predetermined pose in an anatomical coordinate frame; and an intra-operative computing unit in communication with the sensor.
Abstract: Provided are methods and systems related to computer-assisted joint replacement surgery, and corresponding instrumentation systems. In one example, there is provided a system for guided surgery comprising: a sensor for coupling to a first bone to receive positional signals; a beacon for coupling to an object to provide the positional signals to the sensor, the object comprising one of a second bone and a surgical tool; a patient-specific jig (PSJ) for guiding a relative position of the sensor and the first bone during coupling to position the sensor in a predetermined pose in an anatomical coordinate frame; and an intra-operative computing unit in communication with the sensor, the intra-operative computing unit configured to calculate poses of the beacon with respect to the anatomical coordinate frame utilizing pre-operative data representing the PSJ and display positional information for the object in real time.