Abstract: The physicochemical properties of amorphous forms of frusemide, prepared by spray-drying at 50 or 150 degrees C, and their hygroscopic stability at temperatures of 25 and 40 degrees C, and at 0 and 75% relative humidity were investigated. The glass transition temperature of the amorphous form A was 44.2 degrees C as measured by differential scanning calorimetry, while that of the amorphous form B was 54.4 degrees C. The activation energies for glass transition and crystallization processes were calculated from the differential scanning calorimetry thermograms of amorphous forms A and B, respectively. Stability determined by X-ray diffraction at 0% relative humidity, 25 and 40 degrees C suggested that form B was more stable than form A. However, the stability of form A at 75% relative humidity and 25 and 40 degrees C was similar to that of form B.

Abstract: Objective Solid dispersions of daidzein (DZ) were prepared using tween-80 as the surfactant to improve itsdissolution and solubility. Methods Using tween-80 as the surfactant and polyethylene glycol (PEG)-10000 as thecarrier, solid dispersions of DZ were prepared by solvent method. Infrared spectroscopy (IR) and X-ray diffractionspectroscopy were applied to determine the status of DZ in carriers. Results When appropriate amount of Tween-80was added into the solid dispersion, the dissolution of DZ could be improved obviously. The data of IR showed theabsence of well-defined drug-polymer interactions. The data of X-ray diffraction showed that the drug might exist inthe form of amorphism or molecule in solid dispersions. Conclusion Appropriate amount of Tween-80 couldincrease the dissolution rate of DZ.

Abstract: TiO2 nanotube arrays were fabricated by anodic oxidation in electrolytes containing F- in this paper. To achieve local drug delivery, anodized titanium with nanotube layer structures were loaded with ibuprofen(IBU) using a vacuum drying method in which drug molecules were tiled on the anodized titanium to dry in vacuum drying oven. The morphology and phase of TiO2 nanotube were characterized by means of FE-SEM, XRD, FIRT, respectively. Results indicated IBU were loaded on titania nanotube (220nm inner diameter and 7.3μm deep) layer successfully. But the IBU loading on anatase is more than on amorphism. And different phases with drug loading have the same release process, which was divided into quick release and stable release. Quick release processes about Anatase/IBU are fitted with different equations. We found that the experimental data fit the theoretical first-order curve the best. It suggested that the drug carrier had the properties of sustained release.

Abstract: The invention provides an imaging forming device that includes a fixing device for fixing a toner image on a recording medium. The fixing device includes a hear roller and an oil applying device. The oil applying device is used for applying silicon oil on the heat roller. The image forming device has a system rate 500-1700 mm/sec and uses toner. The toner includes adhesive resin, crystal vibrin and amorphism resin; aliphatic series sulfonamide compound; and toner. Ratio of the height (W) showing aliphatic series sulfonamide compound that is obtained in absorption spectrum by ARR method of infrared spectrophotometer with Fourier to W/R showing amorphism resin height (R) is 0.010-0.040.

Abstract: The polymorphism of flucloxacillin sodium has not been discussed sufficiently so far Flucloxacillin sodium which was crystallized with different solvents, was found to exist in amorphism and three crystal forms (I, II, III) This results were confirmed by infra-red (IR) spectra, thermogravimetry (TG), X-ray diffraction analysis (XRD) and equilibrium solubility It is noticed that form III has very good solubility in phosphate buffer solution, with an average solubility of 086 g (20-40 degrees C) However, more efforts are needed to carry out and decide whether this form can be used for industrial production

Abstract: Several Mg-Cu-Y and Mg-Ni-Gd based amorphous brazing materials were prepared by means of rapid solidification. The amorphous structure was examined by XRD and DSC, glass formation ability and melting feature of the amorphous brazing material were also studied. Results show that the alloys prepared are all amorphous and Mg-Ni-Gd alloy has higher glass formation ability and thermal stability.

Abstract: Provided is a method for preparing an electromagnetic shielding composite material with a ferrum-based amorphism/nanocrystalline strip serving as a patch layer. The method comprises processing steps of (1) plasticating isobutylene-isoprene rubber (IIR) on an open type rubber refining machine for 3-10 minutes, then adding rubber compounding agents (known technology) with fixed types and proportion, mixing for about 15-60 minutes to enable a compound phase to be evenly dispersed in the IIR, mixing plastication rubber with white carbon black with proportion of 4:1-6:1 by mass, and producing an IIR film with thickness of 0.1-1mm; (2) compounding carbon fibers with the IIR film to produce an IIR film/carbon fiber/ IIR film interlayer structure, and sulfide forming in a pressure forming machine with sulfide temperature at 165 DEG C, sulfide time for 1-5 hours and sulfide pressure at 1-10 MPa; and (3) selecting ferrum-based amorphism/nanocrystalline alloy strips under unannealed conditions and with different thicknesses to produce the surface conductive type electromagnetic shielding composite. The method has the advantages that (1) by means of recycle of waste strips, the processing problem of the waste strips can be effectively solved so that the method has high economic benefits and environmental benefits; and (2) the preparation process of the method is simple in process, low in equipment requirement, remarkable in effect and favorable for achieving large-scale industrialized application.

Abstract: This article describes the genesis of amorphous silica under high-heat conditions from SiO2 molecules through protoparticles, primary particles, and aggregates to agglomerates using vibrational spectra and quantum chemical simulations data. The impact of small molecules (water, HCl, CO2) is also discussed. The article also explains the nature of the pyrogenic silica amorphism.