About: alpha-Cyclodextrin is a research topic. Over the lifetime, 31 publications have been published within this topic receiving 1025 citations. The topic is also known as: Cyclohexa-Amylose & α-cyclodextrin.
TL;DR: Hydrogen bonds (S146) and hydrophobic contacts (Y89) appear to contribute strongly to the size of cyclodextrin products formed and thus to CGTase product specificity, and changes in sugar binding subsites -3 and -7 thus result in mutant proteins with changed cyclodesxtrin production specificity.