Topic
Adenosine triphosphate
About: Adenosine triphosphate is a research topic. Over the lifetime, 9797 publications have been published within this topic receiving 448338 citations. The topic is also known as: 5'-ATP & adenosine 5' triphosphate.
Papers published on a yearly basis
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Papers
TL;DR: Related sequences in both alpha and beta and in other enzymes that bind ATP or ADP in catalysis help to identify regions contributing to an adenine nucleotide binding fold in both ATP synthase subunits.
Abstract: The alpha- and beta-subunits of membrane-bound ATP synthase complex bind ATP and ADP: beta contributes to catalytic sites, and alpha may be involved in regulation of ATP synthase activity. The sequences of beta-subunits are highly conserved in Escherichia coli and bovine mitochondria. Also alpha and beta are weakly homologous to each other throughout most of their amino acid sequences, suggesting that they have common functions in catalysis. Related sequences in both alpha and beta and in other enzymes that bind ATP or ADP in catalysis, notably myosin, phosphofructokinase, and adenylate kinase, help to identify regions contributing to an adenine nucleotide binding fold in both ATP synthase subunits.
5,603 citations
TL;DR: An electrostatic spray apparatus and method for spraying electrically conductive coating materials on a continuous basis from an electrically grounded bulk coating supply.
2,463 citations
TL;DR: Pulsed ATP/depletion/repletion experiments showed that ATP generation either by glycolysis or by mitochondria was required for the active execution of the final phase of apoptosis, which involves nuclear condensation and DNA degradation.
Abstract: Apoptosis and necrosis are considered conceptually and morphologically distinct forms of cell death Here, we report that demise of human T cells caused by two classic apoptotic triggers (staurosporin and CD95 stimulation) changed from apoptosis to necrosis, when cells were preemptied of adenosine triphosphate (ATP) Nuclear condensation and DNA fragmentation did not occur in cells predepleted of ATP and treated with either of the two inducers, although the kinetics of cell death were unchanged Selective and graded repletion of the extramitochondrial ATP/pool with glucose prevented necrosis and restored the ability of the cells to undergo apoptosis Pulsed ATP/depletion/repletion experiments also showed that ATP generation either by glycolysis or by mitochondria was required for the active execution of the final phase of apoptosis, which involves nuclear condensation and DNA degradation
1,978 citations
TL;DR: Hydrolysis of the labeled ATP with heavy meromyosin indicates that 98 to 99% of the /sup 32/P is in the 1 -phosphate group.
Abstract: A method is described for preparing /sup 32/P-labeled ATP of high specific activity by an excbange reaction The method is simple and requires only substrates and enzymes that are available commercially Hydrolysis of the labeled ATP with heavy meromyosin indicates that 98 to 99% of the /sup 32/P is in the 1 -phosphate group (auth)
1,866 citations
TL;DR: An attempt is made to understand how cross-talk between parallel phosphotransfer pathways can provide a global regulatory curcuitry.
1,712 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2025 | 56 |
| 2024 | 89 |
| 2023 | 176 |
| 2022 | 283 |
| 2021 | 159 |
| 2020 | 158 |