Topic
Actaea asiatica
About: Actaea asiatica is a research topic. Over the lifetime, 13 publications have been published within this topic receiving 65 citations.
Papers
TL;DR: Three new 9,19-cycloartane triterpene glycosides were isolated from the roots/rhizomes extract of Actaea asiatica and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR).
Abstract: Three new 9,19-cycloartane triterpene glycosides, asiaticoside A (1), asiaticoside B (2), and 25-O-ethylcimigenol-3-O-β-d-xylopyranoside (3), together with cimiacemoside I (4), 25-O-acetylcimigenol-3-β-O-d-xyloside (5), and 25-anhydrocimigenol-β-O-d-xyloside (6) were isolated from the roots/rhizomes extract of Actaea asiatica, and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR). Compounds 1−3, 5, and 6 had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.
39 citations
TL;DR: Six new cycloartane triterpene glycosides, isolated from the rhizomes of Actaea asiatica, exhibited positive cytotoxic activities.
5 citations
Journal Article•
TL;DR: In this paper, cycloartane triterpeniods were isolated and identified to be 25-anhydrocimigenol-3-O-β-D-xylopyranoside (Ⅰ), 25-Oacetyl cimicigenol, 3-Oα-L-arabinopyrano-naphrinol (3-α-Naphrin), cimigenola-3.
Abstract: Objective To isolate and elucidate the antitumor constituents from the rhizoma of Actaea asiatica. Methods Chemical constituents were isolated by repeated column chromatography (Toyopearl HW-40C and HPLC) and their structures were elucidated on the basis of spectral data analysis. Results Seven cycloartane triterpeniods were isolated and identified to be 25-anhydrocimigenol-3-O-β-D-xylopyranoside (Ⅰ), 25-O-acetyl cimicigenol-3-O-β-D-xylopyranoside (Ⅱ), cimigenol-3-O-α-L-arabinopyranoside (Ⅲ), cimigenol-3-O-β-D-xylopyranoside (Ⅳ), 3′-O-acetyl cimigenol-3-O-β-D-xylopyranoside (Ⅴ), 24-O-acetyl shengmanol-3-O-β-D-xylopyranoside (23R, 24R) (Ⅵ), 24-O-acetyl isodahurinol-3-O-β-D-xylopyranoside (Ⅶ), respectively. Conclusion Compounds Ⅰ-Ⅶ are isolated from A. asiatica for the first time. Compounds Ⅰ and Ⅱ show significant inhibitory effects on HeLa and L929 cell lines of mice at the concentration of 30 μg/mL.
4 citations
Journal Article•
4 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2021 | 1 |
| 2015 | 1 |
| 2009 | 1 |
| 2008 | 2 |
| 2007 | 3 |
| 2006 | 3 |