TL;DR: The emerging evidence to support the hypothesis that pregnancy outcome in terms of birth weight is linked to the infant's subsequent health is reviewed, potential mechanisms are addressed and potential clinical implications are discussed.
TL;DR: Educating the patient and taking a team approach with the obstetrician will help achieve successful outcomes for mother and baby and Understanding the literature and its limitations is important in the modern era of IBD care.
Abstract: Crohn’s disease and ulcerative colitis affect women in their child-bearing years. Family planning has come to be a common discussion between the gastroenterologist and the inflammatory bowel disease (IBD) patient. Disease control prior to desired conception and throughout pregnancy is the most important thing to keep in mind when caring for the IBD patient. Continued medical management during pregnancy is crucial in optimizing outcomes. Studies indicate that quiescent disease prior to conception infer the best pregnancy outcomes, similar to those in the general population. Active disease prior to and during pregnancy, can lead to complications such as pre-term labor, low birth weight, and small for gestational age infants. Although there are no definitive long term effects of pregnancy on IBD, there are some limited studies that suggest that it may alter the disease course. Understanding the literature and its limitations is important in the modern era of IBD care. Educating the patient and taking a team approach with the obstetrician will help achieve successful outcomes for mother and baby.
TL;DR: Evidence that maternal stress and distress during pregnancy affect fetal growth, pose risk of adverse birth outcomes, mainly preterm birth and low birth weight, and predict poorer developmental and health outcomes over the lifespan is reviewed.
Abstract: We review evidence that maternal stress and distress during pregnancy affect fetal growth, pose risk of adverse birth outcomes, mainly preterm birth and low birth weight, and predict poorer developmental and health outcomes over the lifespan. In addition, we describe the forms of stress shown to be harmful, how they are measured, and briefly review behavioral and physiological mechanisms that may explain the impact of prenatal stress. Furthermore, we discuss some maternal characteristics and interventions that may protect against maternal stress, highlight directions for further investigation, and offer recommendations to women to alleviate stress and its effects in pregnancy.
TL;DR: Whatever the cause of the risks to pregnancy, the goals of managing high-risk pregnancies are to optimize maternal, fetal and perinatal health, so as to maintain maternal health throughout pregnancy and lactation and maximize the number of healthy pups surviving to weaning age.
TL;DR: The rise in obesity among pregnant women goes hand in hand with the upward trend of obesity in the general population, and the percentage of women gaining excessive weight during pregnancy has also increased.
Abstract: Recent years have witnessed a worldwide increase in the prevalence of pre-pregnancy maternal obesity. A survey carried out in the USA between 2003 and 2006 reported that 32% of women aged 20-44 years were classified as obese (WHO 2009).1 The rise in obesity among pregnant women goes hand in hand with the upward trend of obesity in the general population. In addition, the percentage of women gaining excessive weight during pregnancy has also increased.2,3