Topic
Abnormal bone structure
About: Abnormal bone structure is a research topic. Over the lifetime, 10 publications have been published within this topic receiving 373 citations.
Papers
TL;DR: Bone scans are frequently more sensitive than roentgenographic bone surveys for detection of metastatic bone disease, but false-negative results for a variety of reasons, and positive findings must be interpreted with caution.
Abstract: Radioisotope bone scanning is frequently used as the major, and sometimes the only, diagnostic test for neoplasia in bone. While the evidence is convincing that bone scans are frequently more sensitive than roentgenographic bone surveys for detection of metastatic bone disease, there are false-negative results for a variety of reasons, and positive findings must be interpreted with caution. Scans also appear more limited than roentgenograms in their usefulness for evaluating changes in abnormal bone structure. Case histories and discussion are offered to indicate that usually both radioisotope bone scans and roentgenographic bone surveys should be obtained for initial screening and subsequent assessment of bone metastases.
35 citations
TL;DR: The definition, causes sign, diagnosis, pathophysiology, and treatment of both osteoporosis, and osteomalacia are discussed.
Abstract: All vital process in human life as walking, jumping, working, and enjoy with good life apply healthy bone. The normal bone formation required significant amount of some minerals as calcium and phosphorous, also vitamin D which play important role in movement of calcium in to bone which responsible for bone healthy. There are different causes include life style, genetics, hormonal, and insufficient amount take from calcium and vitamin D which responsible for defect in bone formation process, and appear abnormal bone structure. The most bone diseases are osteoporosis, and osteomalacia in this work we discuss the definition, causes sign, diagnosis, pathophysiology, and treatment of both osteoporosis, and osteomalacia.
14 citations
TL;DR: Bone scintigraphy proved valuable in diagnosing McCune-Albright's syndrome in a 6-year-old girl by detecting multiple, non-symptomatic foci in the skull, axial skeleton and in the extremities.
Abstract: Bone scintigraphy proved valuable in diagnosing McCune-Albright's syndrome in a 6-year-old girl by detecting multiple, non-symptomatic foci in the skull, axial skeleton and in the extremities. Subsequent roentgen examination showed abnormal bone structure in the affected areas, consistent with fibrous dysplasia.
7 citations
TL;DR: The treatment of Paget’s disease of bone has entered a new era with the development of newer and more potent bisphosphonate drugs—agents capable of actually “turning off” the pagetic bone remodeling abnormality for extended periods in many patients—physicians can now think about the indications for treatment in a new way.
5 citations
Journal Article•
TL;DR: The viral origin of Paget's bone disease is supported by immunocytological and molecular hybridization studies, and genetic and environmental elements may be involved, favouring and modulating the expressivity of this slow virus infection.
Abstract: Paget's bone disease is a chronic and usually benign bone disorder mainly found in people over fifty The condition is characterized by excessive bone remodelling related to bone cell overactivity leading to abnormal bone structure The viral origin of the disease, first proposed on the basis of ultrastructural observations, is now supported by immunocytological and molecular hybridization studies Genetic and environmental elements may be involved, favouring and modulating the expressivity of this slow virus infection
4 citations
Related Topics (5)
Performance Metrics
| Year | Papers |
|---|---|
| 2017 | 1 |
| 2013 | 1 |
| 1999 | 1 |
| 1997 | 3 |
| 1989 | 1 |
| 1986 | 1 |