About: 4-Methylthioamphetamine is a research topic. Over the lifetime, 3 publications have been published within this topic receiving 103 citations. The topic is also known as: 4-MTA.
TL;DR: MTA is a potent, selective, serotonin releaser, apparently devoid of serotonin neurotoxic effects, which supports the idea that catecholamine systems may play a critical role in the neurotoxicity of PCA-like compounds.
TL;DR: It is suggested that MTA and MMAI might serve as leads for a novel family of compounds with a short onset of action useful for treating depression.
TL;DR: Both 4- methylthioamphetamine and 4-methylthiomethamphetamine are potent inhibitors of [3H]5-HT reuptake in the brain and vasculature in vitro, and unlike MDMA, they both directly inhibit 5-HT-mediated vascular contraction.