Format your manuscript to the Nature Metabolism requirements — abstract, Nature superscript-numbered references, and required declarations — and submit through the Nature online submission system without a formatting rejection.
4.3
Authored by Sumalatha Gangadhar | Published on 19 August, 2026
Most manuscripts sent to Nature Metabolism don’t stumble on the science — they stumble on formatting caught at the first editorial check. This template is built around Nature Metabolism’s actual requirements — its abstract rules, Nature superscript-numbered references, and the required declarations — so your submission clears screening on the first pass. Everything below tracks the Nature Metabolism author guidelines; check it directly if anything looks out of date by the time you submit.
It’s a manuscript shell set up to Nature Metabolism’s specifications for metabolism research across physiology, disease, and molecular mechanism. Nature Metabolism is published by Springer Nature Portfolio). The shell covers the title page, the abstract, a body in Introduction, Methods, Results, and Discussion (IMRaD) order, and a reference list in Nature superscript-numbered style.
Start with the title page (authors, affiliations, and ORCID iDs). The abstract is an unstructured summary paragraph of about 150–200 words written for a broad audience. The body follows Introduction, Methods, Results, and Discussion (IMRaD), and the reference list uses Nature superscript-numbered. Close with the declarations block: ethics approval, conflict of interest, funding, and data availability.
The details that trip up most first submissions: submitting without the required cover letter and a clear editorial summary, a summary paragraph that runs past ~200 words, and figures that don't meet the Nature size and format specs. Beyond that, match your article type’s specific limits rather than assuming the defaults apply, keep Nature superscript-numbered formatting consistent from the first draft, and submit only through the Nature online submission system — email submissions aren’t processed.
The shell mirrors what Nature Metabolism’s editorial staff check first: abstract format and length, Nature superscript-numbered reference formatting, and a complete declarations block. For the journal’s full aims and scope, see the Nature Metabolism journal home page. Nature Metabolism offers an open-access option; check the current article-processing charge and any waiver before you commit. Manuscripts go in through the Nature online submission system, which also tracks your paper through peer review.
| Element | Nature Metabolism requirement |
|---|---|
| Abstract | an unstructured summary paragraph of about 150–200 words written for a broad audience |
| Main text | Introduction, Methods, Results, and Discussion (IMRaD) |
| Declarations | Ethics approval, conflict of interest, funding, and data availability |
| Figures / tables | Captioned, cited in order; check format and resolution rules in the guide |
| Supplemental | Large datasets, extra tables, code — uploaded separately and cited in text |
| Submission | the Nature online submission system |
Read the Nature Metabolism author guidelines once before drafting and once before upload. Draft the abstract after your results are stable so it matches the paper. Set Nature superscript-numbered as your reference style before adding a single citation — retrofitting it later is where errors creep in.
Skim two or three recent Nature Metabolism papers to calibrate depth, structure, and figure style. State your contribution in the first two paragraphs, not on page ten. Write a data-availability statement that names a real repository rather than a placeholder, and disclose any preprint or conference version with identifiers in your cover letter. Confirm current open-access pricing and any institutional agreement before committing to a fee.
Do one focused pass against the Nature Metabolism author guidelines: scope fit, abstract format, length, Nature superscript-numbered references, required declarations, and figure quality. Re-check the items that most often cause a bounce here — submitting without the required cover letter and a clear editorial summary, a summary paragraph that runs past ~200 words, and figures that don't meet the Nature size and format specs. Then submit through the Nature online submission system.