Get your Clinical Therapeutics paper right the first time: a ready-made structure with the right abstract and citations, so editors see your science, not formatting slips.
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Authored by Sumalatha Gangadhar | Published on 7 August, 2026
Submitting to Clinical Therapeutics goes smoothly when your draft already matches the journal's own rules. Editors screen new manuscripts against the Clinical Therapeutics guide for authors before peer review, so formatting, structure, and required statements should be right on the first draft rather than repaired during upload. This template sets that structure up for you.
It is a manuscript shell aligned to Clinical Therapeutics. It covers front matter, the abstract the journal expects, a body organized to the journal's article types, and a reference list in the journal's required style. Confirm current scope and article types on the Clinical Therapeutics journal page before you draft.
Prepare the title, authors, affiliations, and ORCID iDs. Write the abstract to the journal's rule and word limit, organize the body to the article type, and apply the required reference style from the first citation. Complete every declaration (ethics, competing interests, funding, data availability) the Clinical Therapeutics guide for authors lists, and cite figures and tables in order.
The common failure modes are formatting or reference style that does not match the guide for authors, missing required statements, and an incomplete portal checklist. Clear all three against the Clinical Therapeutics guide for authors before you submit.
The shell mirrors what editorial staff check first: article-type fit, the abstract rules, required declarations, and the journal's reference style. For more detail see the author resources. When your draft is ready, upload it through Editorial Manager.
| Element | Clin Ther requirement |
|---|---|
| Abstract | Structured abstract required for Original Research, Systematic Reviews, Narrative Reviews, Brief Reports, and Pilot Studies. Unstructured abstract for Commentaries. No abstract for Research Letters, Case Reports, and Letters to the Editor. Word limits: ≤400 words for Original Research and all Reviews; ≤300 words for Commentaries; ≤250 words for Brief Reports and Pilot Studies. The general guideline states abstracts should briefly state the purpose of research, principal results and major conclusions. While specific headings are not explicitly stated in the guide, the article refers to 'structured (See Abstract)' and main text structures suggest standard IMRAD-style headings are expected (Background/Objective, Methods, Results, Conclusions) |
| Main text | Original Research: ≤6000 words (Introduction, Participants and Methods, Results, Discussion, Conclusions). Systematic Reviews: ≤6000 words (Introduction, Methods, Results, Discussion, Conclusions). Narrative Reviews: ≤6000 words (Introduction, Methods, Results [optional], Discussion, Conclusions). Commentaries: 3000-3500 words (Introduction, Discussion, Conclusions). Brief Reports: 2000-3000 words (Introduction, Methods, Discussion, Conclusions). Pilot Studies: 2000-3000 words (Introduction, Methods, Discussion, Conclusions). Research Letters: 1000-2000 words (Introduction, Methods, Discussion, Conclusions). Case Reports: 1500-3500 words (Introduction, Case Description, Discussion, Conclusions). Letters to the Editor: ≤1000 words, unstructured |
| Declarations | Ethics approval/consent as applicable; competing interests; funding; data availability |
| Figures/tables | Publication-ready; cited in order |
| Supplemental | Upload separately when used |
| Keywords | 4-6 terms required for Original Research, all Reviews, Commentaries, Brief Reports, Pilot Studies, Research Letters, and Case Reports. No keywords for Letters to the Editor. General guideline states 1-7 keywords acceptable for indexing purposes, preferably avoiding multiple-word keywords with 'and' or 'of', and using abbreviations only if firmly established |
| References | Numbered reference style (Vancouver format). References cited in abstract must be given in full. In-text citations use author(s) and year(s) in abstract; numbered citations in main text. Example format provided: 'Naranjo CA, et al. A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-245'. DOIs encouraged. No limit for Original Research and Reviews; ≤60 for Commentaries; ≤30 for Brief Reports, Pilot Studies, and Research Letters; ≤15 for Case Reports; ≤5 for Letters to the Editor |
| Peer review | Single anonymized review (single-blind). The guide states: 'This journal follows a single anonymized review process.' Submissions are initially assessed by editors for suitability, then typically sent to a minimum of two reviewers for independent expert assessment of scientific quality |
| Submission | www.editorialmanager.com/clinther/default.aspx |
Read the Clinical Therapeutics guide for authors once before drafting and once before upload. Draft the abstract after results are stable. Set the reference style before adding citations. Keep a cover letter that states your contribution and fit to Clinical Therapeutics in under a page.
Skim two or three recent Clin Ther papers to calibrate depth and figure style. Make the novelty clear in the first two pages. Deposit data and code when the policy on the Clinical Therapeutics journal page requires it. Disclose any preprint or conference version with identifiers in the cover letter.
Do one focused pass against the Clinical Therapeutics guide for authors: scope, length, reference style, required declarations, and figure quality. Then submit through Editorial Manager.