Journal Article10.1016/J.JCIS.2014.01.016
Zwitterionic hyperbranched polyester functionalized cardiovascular stent and its biocompatibility.
Xiaobo Wang,Jingjing Miao,Xiaobao Shao,Chun Mao,Jian Shen +4 more
- 15 Apr 2014
- Vol. 420, pp 88-96
24
TL;DR: The modified BMS surface does not cause platelets adherent, red blood cell disruption, hemolysis and does not induce complement and platelets activation, and has the potential use for biomedical applications.
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Abstract: Zwitterionic hyperbranched polyester (HBPE) synthesized on bare metal stents (BMS) surface by surface-initiated atom transfer radical polymerization (SI-ATRP) method. The modified BMS obtained was tested for its blood compatibility. The blood compatibility studies were including, platelet adhesion tests, hemolysis assay, morphological changes in RBCs, coagulation tests, PRT assay, complement activation, platelet activation, and the cytotoxicity was also investigated. The modified BMS surface does not cause platelets adherent, red blood cell disruption, hemolysis and does not induce complement and platelets activation. All results indicated that the modified BMS was blood compatible and no cytotoxicity. It has the potential use for biomedical applications.
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Citations
Surface-Initiated Controlled Radical Polymerization: State-of-the-Art, Opportunities, and Challenges in Surface and Interface Engineering with Polymer Brushes
Justin Orazio Zoppe,Nariye Cavusoglu Ataman,Piotr Mocny,Jian Wang,John Moraes,Harm-Anton Klok +5 more
TL;DR: The generation of polymer brushes by surface-initiated controlled radical polymerization (SI-CRP) techniques has become a powerful approach to tailor the chemical and physical properties of interfaces and has given rise to great advances in surface and interface engineering as mentioned in this paper.
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Zwitterionic Biomaterials.
Qingsi Li,Chiyu Wen,Jing Yang,Xianchi Zhou,Ying-Lan Zhu,Jie Zheng,Gang Hu Cheng,Jie Bai,Tong Xu,Jian Ji,Shaoyi Jiang,Lei Zhang,Peng Zhang +12 more
TL;DR: A comprehensive and panoramic overview of zwitterionic polymers can be found in this paper , covering the fundamentals of hydration and nonfouling behaviors, different types of ZW surfaces and polymers, and their biomedical applications.
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Current development of geopolymer as alternative adsorbent for heavy metal removal
TL;DR: In this article, a review of the current development of a potential alternative adsorbent, namely geopolymer, in removing heavy metal pollutants from water via adsorption techniques is presented.
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Platelet-derived nanomotor coated balloon for atherosclerosis combination therapy.
TL;DR: The results indicate that the drug-loaded porous nanomotors proposed for drug balloon coating in this work can penetrate into the plaque and enhance the drug retention efficiency, realizing short-term photothermal elimination of inflammatory macrophages and long-term anti-proliferation effect of the drug.
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A robust mussel-inspired zwitterionic coating on biodegradable poly(L-lactide) stent with enhanced anticoagulant, anti-inflammatory, and anti-hyperplasia properties
Umarova M.,Li Yang,Haoshuang Wu,Yuqi Liu,Qiongfen Xia,Yuan Yang,Nuoya Chen,Ming Yang,Rifang Luo,Gongyan Liu,Yunbing Wang +10 more
TL;DR: Due to the specific characteristics of the mussel–inspired PCBDA/PDA–PEI coating, anticoagulation, anti–inflammatory, and anti–proliferation properties were obtained; thus, it is expected that this coating can be used to inhibit restenosis and realize endothelialization after stent implantation.
56
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