Open AccessJournal Article
Traumatic brain injury due to gunshot wounds: a single institution's experience with 442 consecutive patients.
TL;DR: Low GCS scores, ventricular injuries and bihemispheric injuries are correlated with poor prognosis, and early and less invasive surgery in conjunction with short transportation time to the hospital could decrease mortality rates.
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Abstract: AIM: Traumatic brain injury (TBI) caused by a gunshot wound is a complex injury with a broad spectrum of symptoms and high rates of mortality and morbidity. This study presents an evaluation of TBI caused by gunshot wounds presenting at a single institution and discusses possible predictive factors for the outcome of surgical intervention. MATERIAL and METHODS: The study sample consisted of 442 patients who underwent surgery for TBI over a 16-year period. All injuries were caused by gunshot wounds, such as bullets and shrapnel. All patients underwent surgical intervention. RESULTS: Almost all patients (99.3%) were male, and the mean patient age was 22.3 years. Wounds were caused by shrapnel in 68 percent of patients. The Glasgow Coma Scale (GCS) score at admission was below 8 in 116 patients (26.2%) and above 8 in 326 patients (73.8%). In total, 47 patients (10.6%) died despite surgical management, with diffuse brain injury the most common cause of death. CONCLUSION: Low GCS scores, ventricular injuries and bihemispheric injuries are correlated with poor prognosis. Early and less invasive surgery in conjunction with short transportation time to the hospital could decrease mortality rates. Language: en
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Citations
Epidemiology of traumatic brain injury in Brazil
Raimundo Nonato Ribeiro Fernandes,Marlene Silva +1 more
- 01 Sep 2013
TL;DR: Estudos epidemiológicos robustos sobre o TCE no Brasil ainda sao escassos são urgentemente recomendados.
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- 01 Jan 1989
TL;DR: Les victimes de la guerre Iran-Irak ayant presente une blessure cranienne par projectile and ayant developpe une infection meningee ou cerebrale ont ete suivis pendant plusieurs annees.
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A novel mouse model of penetrating brain injury.
TL;DR: The results showed that this model is capable of reproducing major morphological and neurological changes of pTBI; as such, it is recommended for utilization in research studies aiming to unravel the biological events underlying injury and regeneration after p TBI.
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Bumetanide Prevents Brain Trauma-Induced Depressive-Like Behavior
Emmanuelle Goubert,Marc Altvater,Marie-Noelle Rovira,Ilgam Khalilov,Morgane Mazzarino,Anne Sebastiani,Michael K. E. Schaefer,Claudio Rivera,Claudio Rivera,Christophe Pellegrino +9 more
TL;DR: This work finds a strong suppressive effect of the sodium-potassium-chloride importer (NKCC1) specific antagonist bumetanide on the appearance of depressive-like behavior and demonstrates that this alteration in behavior is associated with an impairment of post-traumatic secondary neurogenesis within the dentate gyrus of the hippocampus.
The Golden Hour After Injury Among Civilians Caught in Conflict Zones
Joseph D. Forrester,Auriel August,Lawrence Z Cai,Adam L. Kushner,Adam L. Kushner,Sherry M. Wren +5 more
TL;DR: Anticipated transport times have important implications for field triage of injured persons in civilian conflict settings because existing overburdened civilian health care systems may become further overwhelmed if in-hospital health capacity is unable to keep pace with inflow of the severely wounded.
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Charles W. Hoge,Dennis McGurk,Jeffrey L. Thomas,Anthony L. Cox,Charles C. Engel,Carl A. Castro +5 more
TL;DR: Mildtraumatic brain injury occurring among soldiers deployed in Iraq is strongly associated with PTSD and physical health problems 3 to 4 months after the soldiers return home, and after adjustment for PTSD and depression, mild traumatic brain injury was no longer significantly associated with these physical health outcomes or symptoms, except for headache.
Epidemiology of trauma deaths: a reassessment
Angela Sauaia,Frederick A. Moore,Ernest E. Moore,Kathe S. Moser,Regina Brennan,Robert A. Read,Peter T. Pons +6 more
TL;DR: There was an improved access to the medical system, greater proportion of late deaths due to brain injury and lack of the classic trimodal distribution, in the Denver City and County trauma system during 1992.
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Clinical trials in head injury
Raj K. Narayan,Mary Ellen Michel,Beth Ansell,Alex Baethmann,Anat Biegon,Michael B. Bracken,M. Ross Bullock,Sung C. Choi,Guy L. Clifton,Charles F. Contant,William M. Coplin,W. Dalton Dietrich,Jamshid Ghajar,Sean M. Grady,Robert G. Grossman,Edward D. Hall,William Heetderks,David A. Hovda,Jack Jallo,Russell L. Katz,Nachshon Knoller,Patrick M. Kochanek,Andrew I R Maas,Jeannine Majde,Donald W. Marion,A Marmarou,Lawrence F. Marshall,Tracy K. McIntosh,Emmy Miller,Noel Mohberg,J. Paul Muizelaar,Lawrence H. Pitts,Peter Quinn,Gad Riesenfeld,Claudia S. Robertson,Kenneth I. Strauss,Graham M. Teasdale,Nancy Temkin,Ronald F. Tuma,Charles E. Wade,Michael D. Walker,Michael Weinrich,John Whyte,Jack E. Wilberger,A. Byron Young,Lorraine Yurkewicz +45 more
TL;DR: The pathomechanisms of traumatic brain damage, based upon their clinical importance, are discussed and a uniform strategic approach for evaluation of potentially interesting new compounds in clinical trials, to ameliorate outcome in patients with severe head injury, is proposed.
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Computed tomography of shearing injuries of the cerebral white matter.
TL;DR: Changes secondary to shearing injury of the cerebral white matter can be demonstrated on CT and are associated with acute severe neurologic deficits and sequelae.
241
Penetrating craniocerebral injuries in the Israeli involvement in the Lebanese conflict, 1982–1985: Analysis of a less aggressive surgical approach
TL;DR: It is suggested that not only is it unnecessary to reoperate for retained bone fragments, but it may also be possible to temper the initial debridement in an effort to preserve additional cerebral tissue.
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