Transcranial Direct Current Stimulation Facilitates Associative Learning and Alters Functional Connectivity in the Primate Brain.

TL;DR: This is the first study to validate and calibrate current-flow models with in vivo intracranial recordings in humans, providing a solid foundation to target stimulation and interpret clinical trials.

TL;DR: In this paper, the authors demonstrate that tES consistently influences the timing, but not the rate, of spiking activity within the targeted brain region, and that these effects are frequency and location-specific and can reach deep brain structures; control experiments show that they cannot be explained by sensory stimulation or other indirect influences.

TL;DR: It is demonstrated that transcranial electrical stimulation, as typically applied to humans, affects the firing patterns of individual neurons in alert nonhuman primates, which are the best available animal model for the human brain.

TL;DR: Several rhythms and their interplay render neuronal communication effective, precise, and selective in neuronal groups.

TL;DR: The result indicates that top-down and bottom-up signals arise from the frontal and sensory cortex, respectively, and different modes of attention may emphasize synchrony at different frequencies.

TL;DR: A new method for detecting and sorting spikes from multiunit recordings that combines the wave let transform with super paramagnetic clustering, which allows automatic classification of the data without assumptions such as low variance or gaussian distributions is introduced.

TL;DR: In this article, a physiological measure of processing load or mental effort required to perform a cognitive task should accurately reflect within-task, between-task and between-individual variations in processing demands.