Tissue Distribution of Toxicity in a Pufferfish, Arothron firmamentum (“Hoshifugu”)
Yuichi Fuchi,Hiroshi Narimatsu,Satoshi Nakama,Hisafumi Kotobuki,Hidetoshi Hirakawa,Yoshiaki Torishima,Tamao Noguchi,Nobuya Ohtomo +7 more
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TL;DR: The “hoshifugu” pufferfish has been characterized as having equivocal toxicity, but the above results indicate that this species should be re-classified as toxic.
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Abstract: Thirty-one specimens of “hoshifugu” pufferfish, Arothron firmamentum, consisting of 16 males and 15 females were obtained from the coastal seas off Oita and Yamaguchi in the fall of 1990. Muscle, skin, liver, gonad and digestive tract were examined for toxicity by means of the mouse assay method.The toxicity of the skin was at rather weak level and was higher in females than males: the frequency (%) of toxic specimens was 12.5% in males and 33.3% in females, and the maximum lethal potency was 30.6MU/g in males and 43.6MU/g in females. The ovary was more toxic: the frequency (%) of toxic specimens was 80.0% and the maximum lethal potency was 888MU/g. The toxicity of the digestive tract was at weak level, while that of the muscle, liver, and testis was lower than 10MU/g.The “hoshifugu” pufferfish has been characterized as having equivocal toxicity, but the above results indicate that this species should be re-classified as toxic.
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Citations
Tetrodotoxin – Distribution and Accumulation in Aquatic Organisms, and Cases of Human Intoxication
Tamao Noguchi,Osamu Arakawa +1 more
TL;DR: TTX-bearing animals are equipped with a high tolerance to TTX, and thus retain or accumulate TTX possibly as a biologic defense substance, and it also has an exogenous origin, i.e., from organisms consumed as food.
TTX accumulation in pufferfish.
TL;DR: To identify the primary producer of TTX, intestinal bacteria isolated from several TTX-bearers were investigated for their TTX production and demonstrated that some of them could produce TTX.
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Toxic Marine Puffer Fish in Thailand Seas and Tetrodotoxin They Contained
Monrat Chulanetra,Nitat Sookrung,Potjanee Srimanote,Nitaya Indrawattana,Jeeraphong Thanongsaksrikul,Yuwaporn Sakolvaree,Manas Chongsa-nguan,Hisao Kurazono,Wanpen Chaicumpa +8 more
TL;DR: This study is the first to report TTX in L. spadiceus, a new fish species found in Thailand's seas during April to July 2010, and raised a concern for people, not only Thais but also inhabitants of other countries situated on the Andaman coast; consuming puffers of the andaman seas is risky due to potential TTX intoxication.
Role of maternal tetrodotoxin in survival of larval pufferfish.
Shiro Itoi,Miwa Suzuki,Kiyoshi Asahina,Eitaro Sawayama,Junki Nishikubo,Hikaru Oyama,Mitsuki Takei,Nanae Shiibashi,Tomohiro Takatani,Osamu Arakawa,Haruo Sugita +10 more
TL;DR: Results indicate that larvae, which are at the most vulnerable stage in the life of pufferfish, are protected by maternal TTX, which is an extremely potent neurotoxin detected in various taxa.
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Toxicity of the Red Sea pufferfish Pleuranacanthus sceleratus El-Karad
TL;DR: The pufferfish Pleuranacanthus sceleratus (El-Karad) represents serious public health problems, because of its responsibility for many incidents in Egypt, especially in the Suez Gulf, and its toxins were purified and identified using TLC and electrophoresis.
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