Patent
Therapeutic method and composition utilizing antigen-antibody complexation and presentation by dendritic cells
Birgit Schultes,Antoine A. Noujaim,Dean L. Mann +2 more
- 11 May 2001
32
TL;DR: In this article, methods and compositions for use in immunotherapy are presented for exploiting dendritic cells to present an antigen to a patient, particularly where the patient has a disease associated with the antigen.
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Abstract: Disclosed are methods and compositions for use in immunotherapy. These methods and compositions are particularly useful for exploiting dendritic cells to present an antigen to a patient, particularly where the patient has a disease associated with the antigen. The invention provides methods for treating a patient having a disease associated with an antigen. The methods according to the invention comprise combining ex vivo an antigen and an antigen-presenting cell binding agent specific for the antigen, and administering the composition to a patient suffering from a disease associated with the antigen, wherein the patient receives a therapeutic benefit.
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