The potential danger of a solely interferon-gamma release assay-based approach to testing for latent Mycobacterium tuberculosis infection in children

TL;DR: This review provides an overview and critical assessment of TB screening practices that are focused on migrants and visitors from high to low TB incidence countries, including pre-m migration screening and post-migration follow-up of those deemed to be at an increased risk of developing TB.

TL;DR: In this article, a chest X-ray (CXR) has been used for the assessment of asymptomatic adults with tuberculosis (TB) infection in the absence of clinical symptoms.

TL;DR: The concordance between tuberculin skin test (TST) and QuantiFERON®‐TB Gold in‐tube (QFT‐GIT) test, when used in contact screening to diagnose LTBI in asymptomatic children, was evaluated and a significant correlation was observed between age and the IFN‐γ response to the mitogen.

TL;DR: In this article , the performance of parallel LTBI screening with tuberculin skin test (TST) and QuantiFERON-TB Gold In-Tube assays (QFT-GIT) before anti-TNF-α treatment in children with immune-mediated inflammatory disorders in a low TB-burden setting was assessed.

TL;DR: This review provides an overview and critical assessment of TB screening practices that are focused on migrants and visitors from high to low TB incidence countries, including pre-m migration screening and post-migration follow-up of those deemed to be at an increased risk of developing TB.

TL;DR: The concordance between tuberculin skin test (TST) and QuantiFERON®‐TB Gold in‐tube (QFT‐GIT) test, when used in contact screening to diagnose LTBI in asymptomatic children, was evaluated and a significant correlation was observed between age and the IFN‐γ response to the mitogen.

TL;DR: A small but noteworthy number of children with findings suggestive of pulmonary TB in the absence of clinical symptoms are identified in asymptomatic TST/IGRA-positive children with evaluable CXRs.