The microbial pan-genome

TL;DR: A comprehensive bioinformatic analysis of the pangenome and T6SS effector genes in 52 high-quality clinical Pseudomonas aeruginosa genomes was performed in this paper .

TL;DR: The expected impact of newly sequenced genomes on antibacterial discovery and vaccinology is addressed and the factors that could be leading to the increase in the number of draft deposits and the consequent loss of relevant biological information are discussed.

TL;DR: The benefits and limitations of S. cerevisiae-based neurodegenerative disease models are explored and consideration is given to future opportunities the exploitation of these models present, including the use of other yeast species such as Schizosaccharomyces pombe.

TL;DR: Methods used to subtype bacterial organisms based on molecular microbiology techniques are described separately for bacteria, viruses, and parasites following a discussion on what is meant by bacterial "species" and "clones.

TL;DR: Over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors are identified, suggesting substantial oceanic microbial diversity.

TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.