Journal Article10.1016/J.GDE.2005.09.006
The microbial pan-genome
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TL;DR: A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed and the pan-genome, which is composed of a "core genome" containing genes present in all strains, and a "dispensable genome", might be orders of magnitude larger than any single genome.
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About: This article is published in Current Opinion in Genetics & Development. The article was published on 01 Dec 2005. The article focuses on the topics: Minimal genome & Bacterial genome size.
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Citations
Inference of Horizontal Gene Transfer: Gaining Insights Into Evolution via Lateral Acquisition of Genetic Material
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Evolution of Bacterial Genomes under Horizontal Gene Transfer
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TL;DR: This study presents a population genetic model for bacterial genome evolution, incorporating gene gain, loss, and horizontal gene transfer, to explain the high variability in bacterial gene content and pangenome diversity.
Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis.
TL;DR: An update on the understanding of bacterial plurality is provided and potential applications in diagnostics, therapeutics, and vaccinology are discussed based on perspectives provided by the DGH with regard to the evolution of pathogenicity.
Coordinate systems for supergenomes.
TL;DR: Benchmarks on real-life data ranging from bacterial to fly genomes demonstrate the feasibility of computing good common coordinate systems and introduces a collection of heuristic simplifiers to resolve ordering conflicts.
Population Biology of Intestinal Enterococcus Isolates from Hospitalized and Nonhospitalized Individuals in Different Age Groups
Ana P. Tedim,Patricia Ruiz-Garbajosa,Jukka Corander,Concepción M. Rodríguez,Rafael Cantón,Rob J. L. Willems,Fernando Baquero,Teresa M. Coque +7 more
TL;DR: This study offers a novel and comprehensive analysis of enterococcal population landscapes and suggests that E. faecium populations from hospitalized patients and from community-based individuals differ, with a predominance of certain clonal lineages, often in association with elderly individuals, occurring in the hospital setting.
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Phages and the Evolution of Bacterial Pathogens: from Genomic Rearrangements to Lysogenic Conversion
TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.
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