Journal Article10.1016/J.GDE.2005.09.006
The microbial pan-genome
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TL;DR: A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed and the pan-genome, which is composed of a "core genome" containing genes present in all strains, and a "dispensable genome", might be orders of magnitude larger than any single genome.
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About: This article is published in Current Opinion in Genetics & Development. The article was published on 01 Dec 2005. The article focuses on the topics: Minimal genome & Bacterial genome size.
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Citations
Phytopathogen emergence in the genomics era
TL;DR: The two major mechanisms of rapid genome adaptation - horizontal gene transfer and hybridisation - are reviewed and the power that access to expansive gene databases provides in aiding the study of phytopathogen emergence is discussed.
Blueberry and cranberry pangenomes as a resource for future genetic studies and breeding efforts
Alan E. Yocca,Adrian E. Platts,Elizabeth I. Alger,Scott J. Teresi,Molla F. Mengist,Juliana Benevenuto,Luis Felipe V. Ferrão,MacKenzie Jacobs,Michal Babinski,Maria Magallanes-Lundback,Philipp E. Bayer,Agnieszka A. Golicz,Jodi L. Humann,Dorrie Main,Richard V. Espley,David Chagné,Nick W. Albert,Sara Montanari,Nicholi Vorsa,James J. Polashock,Luis Diaz-Garcia,Juan Zalapa,Nahla V. Bassil,Patrício Ricardo Muñoz,Massimo Iorizzo,Patrick P. Edger +25 more
TL;DR: The construction and analysis of the first pangenome for both blueberry and cranberry revealed both crops exhibit great genetic diversity, and the discovery of thousands of genes, not present in the previous reference genomes, will serve as the basis of future research and as potential targets for future breeding efforts.
Beyond the genome: community-level analysis of the microbial world
TL;DR: The importance of a spatiotemporal sampling design, together with a multilevel ‘omic approach and a community analysis strategy (association networks and modeling) to examine and predict interacting microbial communities and their impact on the environment is highlighted.
Beyond genomic variation - comparison and functional annotation of three Brassica rapa genomes: a turnip, a rapid cycling and a Chinese cabbage
Ke Lin,Ningwen Zhang,Edouard Severing,Harm Nijveen,Feng Cheng,Richard G. F. Visser,Xiaowu Wang,Dick de Ridder,Guusje Bonnema +8 more
TL;DR: By analysing genes unique to turnip, evidence for copy number differences in peroxidases is found, pointing to a role for the phenylpropanoid biosynthesis pathway in the generation of morphological variation in B. rapa.
Nutrition or nature: disentangling the complex forces shaping prokaryote pan-genomes
Daniel R. Garza,F. A. Bastiaan von Meijenfeldt,Bram van Dijk,Annemarie Boleij,Martijn A. Huynen,Bas E. Dutilh,Bas E. Dutilh +6 more
TL;DR: This work interpreted pan-reactomes as dynamic pools of metabolic reactions that are potentially gained or lost and simulated the routes along which different lineages lose reactions in alternative environments, allowing us to disentangle metabolic reactions whose presence does not depend on the metabolite composition of the external environment.
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