The microbial pan-genome

TL;DR: The current knowledge of genomics, metabolomics and metabolic engineering of the prevalent Lactobacillus species associated with the production of fermented dairy foods are discussed, opening the possibilities for their future knowledge-based applications.

TL;DR: It is suggested that L. crispatus core proteins could protect the vagina from G. vaginalis and bacterial vaginosis, providing an explanation on how this urogenital species could improve vaginal health.

TL;DR: MSPminer is a computationally efficient software tool that reconstitutes Metagenomic Species Pan-genomes (MSPs) by binning co-abundant genes across metagenomic samples and reveals microorganisms hitherto unknown and brings coherence in the nomenclature of the species of the human gut microbiota.

TL;DR: Polymicrobial interactions with the host in both health and disease is discussed, indicating that their host-associated polymicrobial communities, such as those found in the oral cavity, co-evolved with us and have become an integral part of who the authors are.

TL;DR: Over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors are identified, suggesting substantial oceanic microbial diversity.

TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.