Journal Article10.1016/J.GDE.2005.09.006
The microbial pan-genome
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TL;DR: A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed and the pan-genome, which is composed of a "core genome" containing genes present in all strains, and a "dispensable genome", might be orders of magnitude larger than any single genome.
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About: This article is published in Current Opinion in Genetics & Development. The article was published on 01 Dec 2005. The article focuses on the topics: Minimal genome & Bacterial genome size.
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Citations
Comparative analysis of 31 Streptococcus gallolyticus strains uncovers their potential risks from the perspectives of virulence factors and antibiotic resistance genes
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TL;DR: In this article , a pan-genome analysis of S. gallolyticus was conducted and the results showed that the metabolic ability of these strains preferred glycosides and had a crucial influence on the formation and modification of glycans and glycoconjugates.
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Disclosing the Genetic Footprint of the Bacterial Ecotype Inhabiting the Gut of Homeothermic Hosts through Comparative Metagenomics Studies
Joana Patrícia do Jardim Gonçalves Lima
- 09 Dec 2013
TL;DR: The main goal is to identify the genetic features shared by nonrelated organisms belonging to ecologically similar microbiotas – and ultimately to disclose the genetic footprint of the bacterial ecotype capable of surviving in the gut of homeothermic hosts.
Detection of Genome Sequence Outliers Across Pan-Genomes
Lakshmi Y. Sujeeun,Shakuntala Baichoo,Zahra Mungloo-Dilmohamud,Yasmina Jaufeerally-Fakim +3 more
- 01 Sep 2019
TL;DR: It is demonstrated here that characterizing a pan-genome of a given taxon using sequences generated from different genome projects can misguide subsequent genome comparison studies when a set of incorrect strains is selected as input.
Pan-genomic analyses of Corynebacterium pseudotuberculosis andcharacterization of the biovars ovis and equi through comparative genomics
Siomar de Castro Soares
- 09 Aug 2013
TL;DR: The manuscript structure and author's contributions are described as follows: C. pseudotuberculosis state of the art, biovar ovis, and manuscript Structure and author’s contributions.
A non-adaptive demographic mechanism for genome expansion in Streptomyces
TL;DR: The authors found evidence of genome expansion in Streptomyces sister-taxa and hypothesize that a recent demographic range expansion drove increases in genome size through a non-adaptive mechanism.
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Hervé Tettelin,Vega Masignani,Michael J. Cieslewicz,Claudio Donati,Duccio Medini,Naomi L. Ward,Samuel V. Angiuoli,Jonathan Crabtree,Amanda L. Jones,A. Scott Durkin,Robert T. DeBoy,Tanja M. Davidsen,Marirosa Mora,Maria Scarselli,Immaculada Margarit Y Ros,Jeremy Peterson,Christopher R. Hauser,Jaideep P. Sundaram,William C. Nelson,Ramana Madupu,Lauren M. Brinkac,Robert J. Dodson,M. J. Rosovitz,Steven A. Sullivan,Sean C. Daugherty,Daniel H. Haft,Jeremy D. Selengut,Michelle L. Gwinn,Liwei Zhou,Nikhat Zafar,Hoda Khouri,Diana Radune,George Dimitrov,Kisha Watkins,Kevin J. B. O'Connor,Shannon Smith,Teresa Utterback,Owen White,Craig E. Rubens,Guido Grandi,Lawrence C. Madoff,Dennis L. Kasper,John L. Telford,Michael R. Wessels,Rino Rappuoli,Claire M. Fraser +45 more
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Phages and the Evolution of Bacterial Pathogens: from Genomic Rearrangements to Lysogenic Conversion
TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.
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