Journal Article10.1016/J.GDE.2005.09.006
The microbial pan-genome
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TL;DR: A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed and the pan-genome, which is composed of a "core genome" containing genes present in all strains, and a "dispensable genome", might be orders of magnitude larger than any single genome.
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About: This article is published in Current Opinion in Genetics & Development. The article was published on 01 Dec 2005. The article focuses on the topics: Minimal genome & Bacterial genome size.
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Citations
Identification of hidden N4-like viruses and their interactions with hosts in global metagenomes
Kaiyang Zheng,Yantao Liang,David Paez-Espino,Sijun Huang,Xiao Zou,Chen Gao,Yong Jiang,Hui He,Cui Guo,Hongbing Shao,Hualong Wang,Yeong Yik Sung,Wen-Jye Mok,Li Lian Wong,Yu-Zhong Zhang,Jiwei Tian,Nianzhi Jiao,Curtis A. Suttle,Jianfeng He,Andrew McMinn,Min Wang +20 more
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TL;DR: This study expands the knowledge of N4-like viruses via global metagenomic datasets, reveals the novel ecological and genomic signatures of these viruses and will provide the backbone for further N 4-like virus studies.
Pan-genomic Analysis Identifies the Chinese Strain as a New Subspecies of Xanthomonas fragariae.
Feng Wei,Xia Liang,Jian Cheng Shi,Jingnan Luo,Li-Juan Qiu,Xi-Xuan Li,Li-Juan Lu,Ying-Qiang Wen,Jia-Yue Feng +8 more
TL;DR: It is determined that Chinese strains of X. fragariae are genetically distinct from other strains and can be considered a new subspecies, and the presence of XopD, XopG1, CE8, GT2, and GH121 in Chinese strains may play important roles in the early infection process of Chinese strains.
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Yu Wan,Ryan R. Wick,Ryan R. Wick,Justin Zobel,Danielle J. Ingle,Danielle J. Ingle,Michael Inouye,Michael Inouye,Kathryn E. Holt,Kathryn E. Holt,Kathryn E. Holt +10 more
TL;DR: GeneMates, an R package implementing a network approach to identification of HGcoT using WGS data, is presented, which enables users to test for associations between presence-absence of bacterial genes using univariate linear mixed models controlling for population structure based on core-genome variation.
Genomic Insights into Paucibacter aquatile DH15, a Cyanobactericidal Bacterium, and Comparative Genomics of the Genus Paucibacter.
TL;DR: The genome analysis supported that strain DH15 can effectively destroy Microcystis, possibly due to the specific genes involved in the flagellar synthesis, cell wall degradation, and the production of cyanobactericidal compounds.
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TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.
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Mobile elements: drivers of genome evolution.
TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.
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Phages and the Evolution of Bacterial Pathogens: from Genomic Rearrangements to Lysogenic Conversion
TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.
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