The microbial pan-genome

TL;DR: This work presents an extension of the multichromosomal breakpoint median problem to genomes that have undergone gene gain and loss, and demonstrates that in simulations the hidden breakpoint counts depend strongly on relative rates of inversion and gene gain/loss.

TL;DR: The study shows that MLST having higher discriminatory power can be used as an epidemiological tool for strain discrimination of T. pyogenes and shows that there was higher diversity among cattle strains.

TL;DR: In this article , the authors analyzed the openness of chromosomes and chromids of the two bacteria, Vibrio and Pseudoalteromonas, and compared the genomic openness with that of monopartite genomes in the same order.

TL;DR: Over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors are identified, suggesting substantial oceanic microbial diversity.

TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.