The microbial pan-genome

TL;DR: Analysis against vaccine strain, PW8 portrayed that the amino acid composition of toxin and DtxR in Malaysia’s local strains are well-conserved and there was no functional defect noted, Hence, the change in efficacy of the currently used toxoid vaccine is unlikely to occur.

TL;DR: This paper presents a meta-analyses of selection operating on non-translated intergenic regions of diverse bacterial species in bacteria using a Rapid, Large-Scale Pan-Genome Analysis Tool for Intergenic Regions in Bacteria.

TL;DR: RIBAP (Roary ILP Bacterial core Annotation Pipeline) as discussed by the authors utilizes an integer linear programming (ILP) approach that refines the gene clusters initially predicted by Roary.

TL;DR: Over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors are identified, suggesting substantial oceanic microbial diversity.

TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.