Journal Article10.1016/J.GDE.2005.09.006
The microbial pan-genome
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TL;DR: A decade after the beginning of the genomic era, the question of how genomics can describe a bacterial species has not been fully addressed and the pan-genome, which is composed of a "core genome" containing genes present in all strains, and a "dispensable genome", might be orders of magnitude larger than any single genome.
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About: This article is published in Current Opinion in Genetics & Development. The article was published on 01 Dec 2005. The article focuses on the topics: Minimal genome & Bacterial genome size.
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Citations
Comparative Genomic Analysis of Food-Originated Coagulase-Negative Staphylococcus: Analysis of Conserved Core Genes and Diversity of the Pan-Genome.
TL;DR: Pan-genome analysis of five species of food-originated coagulase-negative Staphylococcus indicates that unique genes have been acquired or lost by convergent evolution within individual strains.
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Genomic Variation Influences Methanothermococcus Fitness in Marine Hydrothermal Systems.
Michael Hoffert,Rika E. Anderson,Julie Reveillaud,Leslie G. Murphy,Ramunas Stepanauskas,Julie A. Huber +5 more
TL;DR: In this paper, the authors examined five Methanothermococcus single cell amplified genomes (SAGs) in conjunction with 15 metagenomes and 10 metatranscriptomes from venting fluids at two geochemically distinct hydrothermal vent fields on the Mid-Cayman Rise in the Caribbean Sea.
Insights into genome evolution, pan-genome, and phylogenetic implication through mitochondrial genome sequence of Naegleria fowleri species
M. Aurongzeb,Yasmeen Rashid,Syed Habib Ahmed Naqvi,Hafiz Muhammad Talha Malik,M. Kamran Azim,Syed Shah Hassan,Muhammad Yasir,Alamgir Karim +7 more
TL;DR: The N. fowleri isolate AY27 has a circular mtDNA (49,541 bp), which harbours 69 genes (46 protein-coding genes, 21 tRNAs and 2 rRNAs) as mentioned in this paper .
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•Dissertation
Whole-genome sequence analysis for pathogen detection and diagnostics
Steven L. Salzberg,Adam M. Phillippy +1 more
- 01 Jan 2010
TL;DR: Novel computational methods that unlock the potential of these diagnostics by efficiently analyzing whole-genome DNA sequences are presented, which provide the ultimate nucleic acid diagnostic, revealing the entire sequence of a genome.
3
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Phages and the Evolution of Bacterial Pathogens: from Genomic Rearrangements to Lysogenic Conversion
TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.
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