The microbial pan-genome

TL;DR: New insights into the genomic variations in haloarchaea are provided and expression of new BR variant having good expression in functional form in E. coli is reported.

TL;DR: A novel in silico comparative genomic framework where the performance of typing methods is assessed on the basis of the discriminatory power of the method as well as the concordance of the methods with a whole-genome phylogeny to design the next generation of high-performance molecular typing methods from whole- genome sequence data.

TL;DR: High-resolution methodology based on pyrosequencing of the bacterial 16S rRNA marker gene was adopted to characterize and compare soil and root-inhabiting bacterial communities, showing that roots of Arabidopsis thaliana are preferentially colonized by Proteobacteria, Bacteroidetes and Actinob bacteria, and each bacterial phylum is represented by a dominating class or family of bacteria.

TL;DR: A systems biology analysis of C. difficile that evaluates strain-specific genotypes and phenotypes to investigate the overall diversity of the species and develops a strain typing method based on similarity of accessory genomes to identify and contextualize genetic loci capable of discriminating between strain groups.

TL;DR: Over 1.2 million previously unknown genes represented in these samples, including more than 782 new rhodopsin-like photoreceptors are identified, suggesting substantial oceanic microbial diversity.

TL;DR: The genomic sequence of six strains representing the five major disease-causing serotypes of Streptococcus agalactiae, the main cause of neonatal infection in humans, was generated and Mathematical extrapolation of the data suggests that the gene reservoir available for inclusion in the S. agalactic pan-genome is vast and that unique genes will continue to be identified even after sequencing hundreds of genomes.

TL;DR: Mobile elements within genomes have driven genome evolution in diverse ways and are becoming useful tools for learning more about genome evolution and gene function.

TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.